Publications
Now showing items 1231-1240 of 1372
Tailoring NK Cell Receptor-Ligand Interactions: An Art in Evolution
(2018)
Recognition and killing of aberrant, infected or tumor targets by Natural Killer (NK) cells is mediated by positive signals transduced by activating receptors upon engagement of ligands on target surface. These stimulatory ...
Taking a hands-on approach: Current perspectives on the effect of hand position on vision
(2015)
An exciting new line of research that investigates the impact of one’s own hands on visual processing has flourished in the past several years. Specifically, several studies have demonstrated that objects near the hands ...
Tau oligomers
(2014)
Neurofibrillary tangles (NFTs) composed of intracellular aggregates of tau protein are a key neuropathological feature of Alzheimer's Disease (AD) and other neurodegenerative diseases, collectively termed tauopathies. The ...
Targeting thyroid cancer microenvironment and epigenetic signalling: new frontiers in cancer endocrinology basic and clinical research
(2014)
This Research Topic is devoted to the understanding of molecular mechanisms of Human Thyroid Cancers. Original research describing functional studies of genetic mutations that shed novel insights into the aetiology and ...
Targeting PI3K/mTOR signaling in cancer
(2014)
The phosphatidylinositol 3-kinase (PI3K)/mTOR pathway integrates signals from growth factors with nutrient signals and other conditions and controls multiple cell responses, including proliferation, survival and metabolism. ...
Time and Causality
(2014)
The problem of how humans and other intelligent systems construct causal representations from non-causal perceptual evidence has occupied scholars in cognitive science for many decades. Most contemporary approaches agree ...
Supraspinal Control of Automatic Postural Responses Which Pathway Does What?
(2017)
Rapid corrective actions, termed automatic postural responses, are essential to counter the destabilizing effect of mechanical perturbations during natural behaviors. Previous research has demonstrated that automatic ...
Surgical Infections
(2018)
Surgical infections are caused by the breakdown of the equilibrium existing between organisms and the host. This may occur after a breach in a protective surface, as occurs after surgical trauma, changes in host resistance, ...
Triage in Conservation
(2018)
Ecosystems and their constituent species the world over face a barrage of ongoing, and often escalating, threats. Conservation efforts aim to reduce the impact of these threats to ensure that global biodiversity continues ...
Tumor Cell/Dendritic Cell Interactions and the Influence of Tumors on Dendritic Cell-mediated Anti-Tumor Immune Responses and Dendritic Cell-Based Tumor Immunotherapies
(2014)
Significant efforts over the last two decades have been made to better understand the factors that control DC maturation and activation and the impact of these processes on overall host immunity. In addition to the ...