Publications
Now showing items 1241-1250 of 1372
Tumor Hypoxia: Impact in Tumorigenesis, Diagnosis, Prognosis and Therapeutics
(2017)
Hypoxic regions have been identified within tumors and its presence has been linked to malignant progression, metastasis, resistance to therapy, and poor clinical outcomes following treatment. Acute and chronic hypoxia are ...
Twenty Years After the Iowa Gambling Task: Rationality, Emotion, and Decision-Making
(2018)
The world is full of uncertainty. In unpredictable circumstances, can emotions facilitate advantageous decision-making? A neuroscience team, led by Antonio Damasio, explored this question using the Iowa Gambling Task (IGT). ...
Type I Chaperonins: Mechanism and Beyond
(2018)
Type I chaperonins are key players in maintaining the proteome of bacteria and organelles of bacterial origin. They are well known for their crucial role in mediating protein folding. For almost three decades, the molecular ...
Type I Interferon in Human Autoimmunity
(2015)
The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical mediator of human autoimmune disease. Type I interferons function ...
The Uncanny Valley Hypothesis and Beyond
(2018)
A field of theory and research is evolving around the question highlighted in the Uncanny Valley Hypothesis: How does high realism in anthropomorphic design influence human experience and behaviour? The Uncanny Valley ...
Understanding Developmental Dyslexia: Linking Perceptual and Cognitive Deficits to Reading Processes
(2016)
Understanding the mechanisms responsible for developmental dyslexia (DD) is a key challenge for researchers. A large literature, mostly concerned with learning to read in opaque orthographies, emphasizes phono-logical ...
Understanding Crohn's Disease: Immunity, Genes and Microbes
(2017)
Crohn's disease (CD) is a chronic, relapsing, inflammatory bowel disease resulting in considerable morbidity and reduced quality of life. Although still under intense debate, CD seems to result from an enhanced and ...
Understanding the Role of Time-Dimension in the Brain Information Processing
(2017)
Optimized interaction of the brain with environment requires the four-dimensional representation of space-time in the neuronal circuits. Information processing is an important part of this interaction, which is critically ...
Understanding the Successful Coordination of Team Behavior
(2017)
In many areas of human life, people perform in teams. These teams’ performances depend, at least partly, on team members’ abilities to coordinate their contributions effectively. This includes the making of decisions and ...
T Cell Regulation by the Environment
(2015)
Naïve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, ...