Publications
Now showing items 521-560 of 1372
The Impact of Systems Medicine on Human Health and Disease
(2017)
Complex diseases including diabetes, neurological disorders and cancer are results from a combination of genetic, environmental and lifestyle factors, and development of new prognostic tools for the treatment of such ...
The Impact of Sensory; Linguistic and Social Deprivation on Cognition
(2017)
Early experience plays a crucial role in determining the trajectory of cognitive development. For example, early sensory deprivation is known to induce neural reorganization by way of adaptation to the altered sensory ...
The Importance of Iron in Pathophysiologic Conditions
(2015)
The iron element (Fe) is strictly required for the survival of most forms of life, including bacteria, plants and humans. Fine-tuned regulatory mechanisms for Fe absorption, mobilization and recycling operate to maintain ...
Improving Bayesian Reasoning: What Works and Why?
(2016)
We confess that the first part of our title is somewhat of a misnomer. Bayesian reasoning is a normative approach to probabilistic belief revision and, as such, it is in need of no improvement. Rather, it is the typical ...
Improving Working Memory in Learning and Intellectual Disabilities
(2016)
The last forty years of research have demonstrated that working memory (WM) is a key concept for understanding higher-order cognition. To give an example, WM is involved in reading comprehension, problem solving and ...
Improving outcomes in cerebral palsy with early intervention: new translational approaches
(2015)
The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials ...
Industrial and Host Associated Stress Responses in Food Microbes. Implications for Food Technology and Food Safety
(2017)
Throughout the food processing chain and after ingestion by the host, food associated bacteria have to cope with a range of stress factors such as thermal and/or non-thermal inactivation treatments, refrigeration temperatures, ...
Inflammation in the CNS: Advancing the Field Using Intravital Imaging
(2017)
Inflammation of the CNS can have devastating, long-lived, and in some cases fatal consequences for patients. The stimuli that can induce CNS inflammation are diverse, and include infectious agents, autoimmune responses ...
Inferior Colliculus Microcircuits
(2015)
The inferior colliculus (IC) is a unique structure in the auditory system, located between the primary auditory nuclei of the brainstem and the thalamus. The existence of the complex neural circuits in the auditory brainstem ...
Information-based methods for neuroimaging: analyzing structure, function and dynamics
(2015)
The aim of this Research Topic is to discuss the state of the art on the use of Information-based methods in the analysis of neuroimaging data. Information-based methods, typically built as extensions of the Shannon Entropy, ...
Inhibitory Function in Auditory Processing
(2015)
There seems little doubt that from the earliest evolutionary beginnings, inhibition has been a fundamental feature of neuronal circuits - even the simplest life forms sense and interact with their environment, orienting ...
Inhibiting PARP as a Strategic Target in Cancer
(2016)
Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant ...
How and Why Does Spatial-Hearing Ability Differ among Listeners? What Is the Role of Learning and Multisensory Interactions?
(2016)
Spatial-hearing ability has been found to vary widely across listeners. A survey of the existing auditory-space perception literature suggests that three main types of factors may account for this variability: - physical ...
How aging affects T lymphocyte-mediated immunity
(2015)
Increasing age has been associated with an insufficient protection following vaccination and an increased incidence and severity of infectious diseases. The predicted acceleration of global population aging will accentuate ...
The HSP70 Molecular Chaperone Machines
(2017)
Members of the HSP70 family form a central hub of the molecular chaperone network, controlling protein homeostasis in prokaryotes and in the ATP-containing compartments of the eukaryotic cells. The heat-inducible form ...
How to improve immune reconstitution in allogeneic hematopoietic stem cell transplantation?
(2015)
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of haematological malignancies as a form of immunotherapy acting through a graft-versus-leukemia (GvL) reaction. This curative ...
HSPs - Ambiguous Mediators of Immunity
(2017)
Heat shock proteins (HSPs) were discovered as polypeptides induced by stress that can be found in all kingdoms of cellular organisms. Their functions were, a first enigmatic and these proteins were thus classified by ...
Hybrid Solutions for the Modelling of Complex Environmental Systems
(2017)
Systems studied in environmental science, due to their structure and the heterogeneity of the entities composing them, often exhibit complex dynamics that can only be captured by hybrid modeling approaches. While several ...
Abiotic Stresses in Agroecology: A Challenge for Whole Plant Physiology
(2017)
Understanding plant responses to abiotic stresses is central to our ability to predict the impact of global change and environmental pollution on the production of food, feed and forestry. Besides increasing carbon dioxide ...
Abiotic Stress Signaling in Plants: Functional Genomic Intervention
(2016)
Abiotic stresses such as high temperature, low-temperature, drought and salinity limit crop productivity worldwide. Understanding plant responses to these stresses is essential for rational engineering of crop plants. In ...
Abiotic Stress: Molecular Genetics and Genomics
(2014)
Abiotic stresses are the major cause that limits productivity of crop plants worldwide. Plants have developed intricate machinery to respond and adapt over these adverse environmental conditions both at physiological and ...
About the Foodborne Pathogen Campylobacter
(2018)
A significant increase in the prevalence of campylobacteriosis cases has been observed over the past years. Campylobacter has emerged as the leading cause of bacterial foodborne disease worldwide with a significant impact ...
Abstract Mathematical Cognition
(2016)
Despite the importance of mathematics in our educational systems little is known about how abstract mathematical thinking emerges. Under the uniting thread of mathematical development, we hope to connect researchers from ...
Accessing Conceptual Representations for Speaking
(2016)
For speaking, words in the lexicon are somehow activated from conceptual representations but we know surprisingly little about how this works precisely. Which of the attributes of the concept DOG (e.g. BARKS, IS WALKED ...
Application of genetically encoded indicators to mammalian central nervous system
(2016)
Genetically encoded indicators emerged as promising tools for cell type-specific and chronic recording of neuronal population activity. Since publication of the first prototypical genetically encoded Ca2+ indicators ...
Acoustical Impact of Ships and Harbours: Airborne and Underwater N&V Pollution
(2019)
Noise and vibrations generated by ships affect a wide range of receivers: crew and passengers inside the vessel, inhabitants of the coastal areas and marine fauna outside it. Recent studies suggest that a large percentage ...
Application of Nonlinear Analysis to the Study of Complex Systems in Neuroscience and Behavioral Research
(2016)
Although nonlinear dynamics have been mastered by physicists and mathematicians for a long time (as most physical systems are inherently nonlinear in nature), the recent successful application of nonlinear methods to ...
Application of Nanotechnology in Food Science and Food Microbiology
(2018)
Nanotechnology is a fast-evolving discipline that already produces outstanding basic knowledge and industrial applications for the benefit of society. It is a new emerging and fascinating field of science, that permits ...
Applications of Quantum Mechanical Techniques to Areas Outside of Quantum Mechanics
(2018)
This book deals with applications of quantum mechanical techniques to areas outside of quantum mechanics, so-called quantum-like modeling. Research in this area has grown over the last 15 years. But even already more than ...
Applications of Novel Analytical Methods in Epidemiology
(2018)
The repertoire of quantitative analytical techniques in disciplines such as ecology, decision science, and evolutionary biology has grown, in part enabled by the development and increased availability of computational ...
Applications of STEM (Science, Technology, Engineering and Mathematics) Tools in Microbiology of Infectious Diseases
(2017)
Epidemiology is a discipline intended to systematically investigate, and ideally quantify, disease dynamics in populations (Perez, 2015). Epidemiological assessmentsmay be divided into four large areas, namely, (a) ...
Applied Olfactory Cognition
(2014)
Foreword by Richard J. Stevenson, Macquarie University (Australia): It was long thought that the human nose might be able to discriminate somewhere in the order of 10,000 different odourants. The recent finding that the ...
Aquaporins: Dynamic Role and Regulation
(2017)
Aquaporins (AQPs), a class of integral membrane proteins, form channels facilitating movement of water and many other solutes. In solute transport systems of all living organisms including plants, animals and fungi, AQPs ...
Archaeal Cell Envelope and Surface Structures
(2016)
Prokaryotes have a complex cell envelope which has several important functions, including providing a barrier that protects the cytoplasm from the environment. Along with its associated proteinaceous structures, it also ...
Advances in Farm Animal Genomic Resources
(2016)
The history of livestock started with the domestication of their wild ancestors: a restricted number of species allowed to be tamed and entered a symbiotic relationship with humans. In exchange for food, shelter and ...
Advances in Epithelial Ovarian Cancer: Model Systems, Microenvironmental Influences, Therapy, and Origins
(2016)
This eBook provides a compendium of the current state-of-the-art in research tools for, and understanding of, the critical research areas in epithelial ovarian cancer (EOC) with a strong emphasis on (HG-SOC). Research areas ...
Advances in Emotion Regulation: From Neuroscience to Psychotherapy
(2017)
Emotions are the gift nature gave us to help us connect with others. Emotions do not come from out of nowhere. Rather, they are constantly generated, usually by stimuli in our interpersonal world. They bond us to others, ...
Is Conflict Adaptation an Illusion?
(2015)
Conflict adaptation theory is one of the most popular theories in cognitive psychology. The theory argues that participants strategically modulate attention away from distracting stimulus features in response to conflict. ...
Is the Language Faculty Non Linguistic?
(2016)
A line of research in cognitive science over several decades has been dedicated to finding an innate, language-specific cognitive system, a faculty which allows human infants to acquire languages natively without formal ...