Publications
Now showing items 601-640 of 1372
Intrinsic Clocks
(2018)
"Intrinsic Clocks" presents an array of current research activities on intrinsic clocks and their contributions to biology and physiology. It elucidates the current models for the intrinsic clocks, their molecular components ...
Investigating and harnessing T-cell functions with engineered immune receptors and their ligands
(2015)
T-cells are an essential component of the immune system that provide protection against pathogen infections and cancer and are involved in the aetiology of numerous autoimmune and autoinflammatory pathologies. Their ...
Investigating the human brainstem with structural and functional MRI
(2014)
The brainstem is one of the least understood parts of the human brain despite its prime importance for the maintenance of basic vital functions. Owing to its role as a relay station between spinal cord, cerebellum and ...
Investigating Human Nature and Communication through Robots
(2017)
The development of information technology enabled us to exchange more items of information among us no matter how far we are apart from each other. It also changed our way of communication. Various types of robots recently ...
Investigating Grammar in Autism Spectrum Disorders
(2018)
Autism Spectrum Disorder (ASD hereafter) is a neurodevelopmental condition characterized by deficits in communicative and social skills. The vast majority of research on language in ASD has focused on pragmatic difficulties, ...
Invisible, but how? The depth of unconscious processing as inferred from different suppression techniques
(2015)
To what level are invisible stimuli processed by the brain in the absence of conscious awareness? It is widely accepted that simple visual properties of invisible stimuli are processed; however, the existence of higher-level ...
Involvements of TRP Channels and Oxidative Stress in Pain
(2018)
Undoubtedly, pain conditions the quality of life of millions of people worldwide suffering a wide range of diseases. Major research efforts are being made by the international scientific community to determine the mechanisms ...
Ionotropic Glutamate Receptors Trafficking in Health and Disease
(2017)
The knowledge about the properties and importance of ionotropic glutamate receptor trafficking is ever increasing. Importantly, the pace of the progress has been accelerated in recent years. Here, our contributors provide ...
Karolinska Institutet 200-Year Anniversary Symposium on Injuries to the Spinal Cord and Peripheral Nervous System - An Update on Recent Advances in Regenerative Neuroscience
(2017)
The present E-book consists of original articles and reviews published in our Research Topic on injuries to the spinal cord and peripheral nerves and presents a wide array of novel findings and in depth discussions on ...
The Janus-Face of Language: Where Are the Emotions in Words and the Words in Emotions?
(2018)
<p>Language has long been considered independent from emotions. In the last few years however research has accumulated empirical evidence against this theoretical belief of a purely cognitive-based foundation of language. ...
Leading people - managing organizations: Contemporary public health leadership
(2015)
In this Research Topic, we provide a comprehensive overview of current public health leadership research, focusing on understanding the impact of leadership on the delivery of public health services. By bringing together ...
Madness and Creativity: Yes, No or Maybe?
(2015)
The pervasive idea that madness and creativity are intricately linked is one that holds tremendous fascination for both scientists and the general public alike. Although this view was at first largely driven by anecdotal ...
Linguistic Influences on Mathematical Cognition
(2017)
For many years, an abstract, amodal semantic magnitude representation, largely independent of verbal linguistic representations, has been viewed as the core numerical or mathematical representation This assumption has been ...
Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants
(2016)
Environmental stresses and metabolic by-products can severely affect the integrity of genetic information by inducing DNA damage and impairing genome stability. As a consequence, plant growth and productivity are irreversibly ...
Magnetoencephalography: an emerging neuroimaging tool for studying normal and abnormal human brain development
(2015)
Research on the human brain development has seen an upturn in the past years mostly due to novel neuroimaging tools that became available to study the anatomy and function of the developing brain. Magnetic Resonance Imaging ...
Manipulative approaches to human brain dynamics
(2015)
In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and ...
Manipulation of the host cell by viral auxiliary proteins
(2015)
Productive HIV infection requires completion of all the steps of the replication cycle, the success of which largely relying on the multiple interactions established by viral proteins with cellular partners. Indeed, cellular ...
Manipulation of the cellular microbicidal response and endocytic dynamic by pathogens membrane factors
(2015)
Intracellular pathogens, such as bacteria and parasites, have evolved specialized mechanisms to survive and replicate in their host, leading to disorders and diseases. The principle of these mechanisms is to reprogram the ...
LuxR Solos are Becoming Major Players in Cell-Cell Communication in Bacteria
(2016)
The most common quorum sensing (QS) system in Gram-negative bacteria occurs via N-acyl homoserine lactone (AHLs) signals. An archetypical system consists of a LuxI-family protein synthesizing the AHL signal which binds at ...
Making Science Fun - A Tribute to Our Colleague and Friend, Prof. Antonius G. Rolink (1953-2017)
(2019)
This Research Topic honors the memory of Prof. Antonius “Ton” G. Rolink (April 19, 1953–August 06, 2017), our colleague, mentor and friend in immunology. It is now over a year since Ton left us. This article collection, ...
Microorganisms for Functional Food
(2016)
Nowadays, most of Western consumers are aware that a targeted diet could be an important tool for fighting ageing and diseases such as hypertension, diabetes, and obesity. Microorganisms may be exploited for setting up ...
Melt Water Retention Processes in Snow and Firn on Ice Sheets and Glaciers: Observations and Modeling
(2018)
Melt takes place where the surface of glaciers or ice sheets interacts with the atmosphere. While the processes governing surface melt are fairly well understood, the pathways of the meltwater, from its origin to the moment ...
Macrocognition: The Science and Engineering of Sociotechnical Work Systems
(2018)
The increasing complexity of work systems and changes in the nature of workplace technology over the past century have resulted in an exponential shift in the nature of work activities, from physical labor to cognitive ...
Language, Cognition and Gender
(2016)
Gender inequality remains an issue of high relevance, and controversy, in society. Previous research shows that language contributes to gender inequality in various ways: Gender-related information is transmitted through ...
A living history of immunology
(2015)
In the highly competitive world of biomedical science, often the rush to publish and to be recognized as "first" with a new discovery, concept or method, is lost in the hurly-burly of the moment, as "the maddening crowd" ...
Liver Myofibroblasts
(2016)
Myofibroblasts (MFB) are found in most tissues of the body. They have the matrix-producing functions of fibroblasts and contractile properties that are known from smooth muscle cells. Fundamental work of the last decades ...
Lateralization and cognitive systems
(2015)
Left-right asymmetries of structure and function are a common organization principle in the brains of humans and non-human vertebrates alike. While there are inherently asymmetric systems such as the human language system ...
Less and Non-invasive Hemodynamic Monitoring Techniques
(2018)
In the perioperative setting and in intensive care medicine, early and effective hemodynamic management including fluid therapy and administration of vasoactive drugs to maintain vital organ perfusion and oxygen delivery ...
Mechanisms of neuroinflammation and inflammatory neurodegeneration in acute brain injury
(2015)
Mechanisms of brain-immune interactions became a cutting-edge topic in systemic neurosciences over the past years. Acute lesions of the brain parenchyma, particularly, induce a profound and highly complex neuroinflammatory ...
Mechanisms underlying firing in healthy and sick human motoneurons
(2015)
Since the latter half of the twentieth century an enormous amount of knowledge about mammalian motoneuron pools has been collected. This progress was enabled mostly by the development of the precise techniques of intracellular ...
Mechanisms of Persistence, Survival, and Transmission of Bacterial Foodborne Pathogens in Production Animals
(2018)
Foodborne illness resulting from food production animals is a global health concern, and the Centers for Disease Control estimate that one in six Americans will become sick with a foodborne illness each year. Of course ...
Mechanisms of Neuronal Migration during Corticogenesis
(2016)
The cerebral cortex plays central roles in many higher-order functions such as cognition, language, consciousness, and the control of voluntary behavior. These processes are performed by the densely interconnected networks ...
Mechanisms of Neural Circuit Formation
(2015)
The formation of the proper pattern of neuronal circuits during development is critical for the normal function of the vertebrate brain and for the survival of the organism. Circuit tracing studies spanning the past 100 ...
Mechanisms Underpinning the Link between Emotion, Physical Health and Longevity
(2017)
The 1990’s was designated as ‘the decade of the brain’ and now, common mental disorders are described as ‘brain disorders’. Yet intense research interest on the brain has largely side-lined the body as a passive observer, ...
Mechanisms of Innate Neuroprotection
(2016)
As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been ...
Microglia in Health and Disease: A Unique Immune Cell Population
(2018)
Microglia are essential for the development and function of the adult brain. Their ontogeny, together with the absence of turnover from the periphery and the singular environment of the central nervous system (CNS), make ...
Microglial Polarization in the Pathogenesis and Therapeutics of Neurodegenerative Diseases
(2018)
Microglia-mediated neuroinflammation is one of the shared prominent hallmarks among various forms of neurodegeneration. Depending on the milieu in which microglia become activated, the polarization of microglia shows to ...
Melatonin in Plants
(2017)
This topic focuses on distribution, synthesis, metabolism, and the in vivo roles of melatonin in plants, with 1 editorial, 3 reviews, 21 original research studies and 1 corrigendum.
Memory Systems of the Addicted Brain: The Underestimated Role of Drug-Induced Cognitive Biases in Addiction and Its Treatment
(2018)
Drug addiction may be viewed as a form of learning during which strong associations linking actions to drug-seeking are expressed as persistent stimulus–response habits, thereby maintaining a vulnerability to relapse. ...
Learning to see (better): Improving visual deficits with perceptual learning
(2015)
Perceptual learning can be defined as a long lasting improvement in a perceptual skill following a systematic training, due to changes in brain plasticity at the level of sensory or perceptual areas. Its efficacy has been ...