Publications
Now showing items 341-360 of 1372
The Evolution of Endothermy - From Patterns to Mechanisms
(2018)
Metabolic rate is a key ecophysiological factor determining fitness, distribution, survival and reproductive strategies of organisms. The ability to endogenously produce heat and elevate body temperature beyond ambient, ...
The Evolution of Rhythm Cognition: Timing in Music and Speech
(2018)
Human speech and music share a number of similarities and differences. One of the closest similarities is their temporal nature as both (i) develop over time, (ii) form sequences of temporal intervals, possibly differing ...
Evolution of Organismal Form: From Regulatory Interactions to Developmental Processes and Biological Patterns
(2017)
Today's biodiversity is the spectacular product of hundreds of millions of years of evolution. Understanding how this diversity of living organisms appeared is one of the most intriguing and challenging question in biology. ...
Evolution of Gene Regulatory Networks in Plant Development
(2018)
During their life cycle plants undergo a wide variety of morphological and developmental changes. Impinging these developmental processes there is a layer of gene, protein and metabolic networks that are responsible for ...
Evolution of Reproductive Organs in Land Plants
(2018)
The great diversity of land plants (especially angiosperms) is mainly reflected in the diversity of various reproductive organs of plants. However, despite long time intensive investigations, there are still uncertainties ...
Epitope Discovery and Synthetic Vaccine Design
(2018)
Since variolation, conventional approaches to vaccine development are based on live-attenuated, inactivated or purified pathogen-derived components. However, effective vaccines against global health threats such as HIV, ...
Educating the Global Workforce for Public Health
(2018)
Good quality management of the health system demands a critical mass of health professionals with sound technical knowledge. The education that produces a workforce of appropriate size and skills is often a challenge in ...
Closed-Loop Systems for Next-Generation Neuroprostheses
(2018)
Millions of people worldwide are affected by neurological disorders which disrupt the connections within the brain and between brain and body causing impairments of primary functions and paralysis. Such a number is likely ...
Closing the Loop Around Neural Systems
(2014)
Closed-loop neurophysiology has been accelerated by recent software and hardware developments and by the emergence of novel tools to control neuronal activity with spatial and temporal precision, in which stimuli are ...
The cognitive and neural organisation of speech processing
(2016)
Speech production and perception are two of the most complex actions humans perform. The processing of speech is studied across various fields and using a wide variety of research approaches. These fields include, but are ...
Cognitive deficits in schizophrenia and other neuropsychiatric disorders: Convergence of preclinical and clinical evidence
(2015)
Neuropsychiatric diseases, such as schizophrenia, Alzheimer's disease, and etc., represent a serious medical and socioeconomic problems. These diseases are often accompanied by impairments of cognitive function, e.g., ...
Cognitive Event-Related Potentials in Psychopathology: New Experimental and Clinical Perspectives
(2017)
A common feature of many psychopathological states (going from anxiety, depression to schizophrenia or addictions) is to show cognitive alterations. These cognitive deficits clearly impact on the onset of clinical symptoms. ...
The Cognitive Neuroscience of Visual Working Memory
(2017)
Visual working memory allows us to temporarily maintain and manipulate visual information in order to solve a task. The study of the brain mechanisms underlying this function began more than half a century ago, with Scoville ...
The Emerging Discipline of Quantitative Systems Pharmacology
(2015)
In 2011, the National Institutes of Health (NIH), in collaboration with leaders from the pharmaceutical industry and the academic community, published a white paper describing the emerging discipline of Quantitative Systems ...
Emerging Functions of Septins
(2017)
Together with the microfilament, microtubule and intermediate-filament networks, septins constitute an integral part of the eukaryotic cytoskeleton. Historically identified as proteins critical for septum formation in the ...
Emerging Enterobacteriaceae Infections: Antibiotic Resistance and Novel Treatment Options
(2017)
Enterobacteriaceae are spread worldwide and the diseases they cause may be fatal especially in immunocompromised patients. Moreover, the high prevalence of ESBL producing Salmonella and Shigella species diseases worldwide ...
Emerging immune functions of non-hematopoietic stromal cells
(2014)
The development and function of the immune system is dependent on interactions between haematopoietic cells and non-hematopoietic stromal cells. The non-hematopoietic stromal cells create the microenvironment in which the ...
Engineering the Plant Factory for the Production of Biologics and Small-Molecule Medicines
(2017)
Plant gene transfer achieved in the early ‘80s paved the way for the exploitation of the potential of gene engineering to add novel agronomic traits and/or to design plants as factories for high added value molecules. For ...
Engineering Synthetic Metabolons: From Metabolic Modelling to Rational Design of Biosynthetic Devices
(2016)
The discipline of Synthetic Biology has recently emerged at the interface of biology and engineering. The definition of Synthetic Biology has been dynamic over time ever since, which exemplifies that the field is rapidly ...