Publications
Now showing items 81-160 of 1372
Cancer Care Delivery and Women's Health
(2017)
Cancer care delivery refers to the multiple layers of the health care system that interact to affect outcomes for patients with cancer and the quality of that care. The factors included in the care delivery system that ...
Cardiovascular Toxicities of Breast Cancer Treatment: Emerging Issues in Cardio-Oncology
(2016)
Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the ...
Cardiac Remodeling: New Insights in Physiological and Pathological Adaptations
(2017)
The effective management of Cardiac remodeling(CR), remains a major challenge. Heart failure remains the leading cause of death in industrialized countries. Yet, despite the enormity of the problem, effective therapeutic ...
The Challenge of Protein Crops as a Sustainable Source of Food and Feed for the Future
(2017)
Grain legumes, together with quinoa and amaranth (pseudocereals) and other crops are attractive candidates to satisfy the growing demand for plant protein production worldwide for food and feed. Despite their high value, ...
Challenges and Opportunities for the EU Common Fisheries Policy Application in the Mediterranean and Black Sea
(2019)
The application of the Common Fisheries Policy (CFP) in the Mediterranean and Black Sea faces several challenges also because of large ecological, economic, political and institutional differences across the basin. The ...
Anthropogenic Impacts on the Microbial Ecology and Function of Aquatic Environments
(2016)
Aquatic ecosystems are currently experiencing unprecedented levels of impact from human activities including over-exploitation of resources, habitat destruction, pollution and the influence of climate change. The impacts ...
Auditory Efferent System: New Insights from Cortex to Cochlea
(2016)
The main function of the sensory systems is the transducing of external stimuli into bioelectrical signals, which are conducted through afferent pathways from sensory epithelia to the brain. However, it is known that ...
Autoimmuno-Anti-Tumour Immunity (AATI) - Understanding the Immune Responses against "Self" & "Altered-self"
(2017)
The brief description of tumours being “wounds that do not heal” by Dr Harold F. Dworak nearly three decades ago (N Engl J Med 1986) has provided not only a vivid illustration of neoplastic diseases in general but also, ...
Advances in Parasitic Weeds Research
(2018)
Parasitic weeds are severe constraint to agriculture and major crop production, and the efficacy of available means to control them is minimal. Control strategies have centred around agronomic practices, resistant varieties ...
Affective Sciences through the Chemical Senses
(2017)
In people's minds, smells, flavors and affective phenomena are perceived as closely linked. But is it genuinely the case? The scientific study of this question is a rapidly expanding field, both in healthy and in clinical ...
The Atmosphere over Mountainous Regions
(2016)
Mountainous regions occupy a significant fraction of the Earth’s continents and are characterized by specific meteorological phenomena operating on a wide range of scales. Being a home to large human populations, the impact ...
Balloon and Stent for Ischemic and Hemorrhagic Stroke: A New Trend for Stroke Prevention and Management
(2015)
In recent years, intracranial endovascular use of Balloon and Stent has grown significantly. This issue will focus primarily on recent advances in the use of these methods today. This discussion will also highlight our ...
Ballroom Biology: Recent Insights into Honey Bee Waggle Dance Communications
(2016)
The honey bee waggle dance communication is a complex, unique, at times controversial, and ultimately fascinating behavior. In an elaborate figure-of-eight movement, a returning forager conveys the distance and direction ...
The CA3 region of the hippocampus: how is it? what is it for? how does it do it?
(2015)
The aim of this special topic is to bring together experts on the cellular and molecular mechanisms regulating the wiring properties of the CA3 hippocampal microcircuit in both physiological and pathological conditions, ...
Aging, neurogenesis and neuroinflammation in hearing loss and protection
(2015)
Worldwide, 278 million people are estimated to have moderate to profound hearing loss. Age-related hearing loss, also known as presbyacusis, affects approximately half of the population over 60 years old, making it the ...
Aging and Mental Health
(2017)
People are progressively ageing all over the world, and it is estimated that the number of persons aged 60 or over will more than triple by 2100. This emerging population will experience an inevitable rise in dementia, ...
CD1- and MR1-restricted T Cells in Antimicrobial Immunity
(2016)
Cell-mediated immunity to extracellular and intracellular microbes has been traditionally linked to CD4+ and CD8+ T cells that recognize pathogen-derived peptides in the context of major histocompatibility complex (MHC) ...
The CB2 Cannabinoid System: A New Strategy in Neurodegenerative Disorder and Neuroinflammation
(2017)
The neurodegenerative disorders such as Parkinson’s disease (PD) or Alzheimer’s disease (AD) are the most common forms of dementia and no pharmacological treatments are to date available for these diseases. Indeed, the ...
Anatomy and Plasticity in Large-Scale Brain Models
(2017)
Supercomputing facilities are becoming increasingly available for simulating activity dynamics in large-scale neuronal networks. On today's most advanced supercomputers, networks with up to a billion of neurons can be ...
Advances in Legume Research
(2018)
Legumes crops have an extraordinary importance for the agriculture and the environment. In a world urgently requiring more sustainable agriculture, food security and healthier diets the demand for legume crops is on the ...
Advances in Virtual Agents and Affective Computing for the Understanding and Remediation of Social Cognitive Disorders
(2016)
Advances in modern sciences occur thanks to within-fields discoveries as well as confrontation of concepts and methods from separated, sometimes distant, domains of knowledge. For instance, the fields of psychology and ...
Biased Cognitions & Social Anxiety: Building a Global Framework for Integrating Cognitive, Behavioral, and Neural Processes
(2015)
Social anxiety (SA) is a common and incapacitating disorder that has been associated with seriously impaired career, academic, and general social functioning. Regarding epidemiological data, SA has a lifetime prevalence ...
Basic and applied research on deception and its detection
(2014)
Deception is a ubiquitous phenomenon in social interactions and has attracted a significant amount of research during the last decades. The majority of studies in this field focused on how deception modulates behavioral, ...
Basal ganglia: physiological, behavioral, and computational studies
(2015)
The basal ganglia has received much attention over the last two decades, as it has been implicated in many neurological and psychiatric disorders. Most of this research - in both animals and humans - attempt to understand ...
Behavioral and physiological bases of attentional biases: Paradigms, participants, and stimuli
(2015)
Attentional biases (ABs) play a prominent role in the development and maintenance of clinically relevant symptoms of, for example, anxiety and depression. In particular, increased attentional orienting and preoccupation ...
Behavioural and Ecological Consequences of Urban Life in Birds
(2018)
Urbanization is next to global warming the largest threat to biodiversity. Indeed, it is becoming increasingly evident that many bird species get locally extinct as a result of urban development. However, many bird species ...
Beyond Borders: Myotonic Dystrophies - A European Perception
(2019)
Myotonic dystrophies (DMs) are pleotropic multisystemic diseases. These dominantly transmitted repeat disorders affect multiple organs of the human body at all ages – from the newborns to the elderly. The present Research ...
Carotid Body: A New Target for Rescuing Neural Control of Cardiorespiratory Balance in Disease
(2016)
The carotid body (CB) is in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other ...
The causes and consequences of microbial community structure
(2015)
The causes and consequences of differences in microbial community structure, defined here as the relative proportions of rare and abundant organisms within a community, are poorly understood. Articles in "The Causes and ...
Central Nervous System Metastases in Lung Cancer Patients: From Prevention to Diagnosis and Treatment
(2019)
Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. ...
Central control of autonomic functions in health and disease
(2015)
The field of autonomic neuroscience research concentrates on those neural pathways and processes that ultimately modulate parasympathetic and sympathetic output to alter peripheral organ function. In the following ebook, ...
Amyloid-beta clearance in Alzheimer's disease
(2015)
Strong evidence continues to accumulate indicating that amyloid-beta (Aß) is a central part of Alzheimer’s disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms ...
Autophagy in plants and algae
(2015)
Autophagy (also known as macroautophagy) is an evolutionarily conserved process by which cytoplasmic components are nonselectively enclosed within a double-membrane vesicle known as the autophagosome and delivered to the ...
Advances in Research on Age in the Workplace and Retirement
(2018)
Shifts in the age composition of the workforce coupled with dynamic definitions of retirement represent important issues that influence work processes and, more generally, the experience of working across one’s career. For ...
Awareness shaping or shaped by prediction and postdiction
(2015)
We intuitively believe that we are aware of the external world as it is. Unfortunately, this is not entirely true. In fact, the capacity of our sensory system is too small to veridically perceive the world. To overcome ...
Avoidance: From Basic Science to Psychopathology
(2016)
Coping has a myriad of facets: knowledge concerning the circumstances of threats to emotional and physical well being, the ability to meet immediate needs to mitigate, the potential for recurrence, the ability to apply ...
Better Together: A Joined-Up Psychological Approach to Health, Well-Being, and Rehabilitation
(2016)
Health and well-being is best understood in terms of a combination of biological, psychological, and social factors. But how ‘social’ is the biopsychosocial model when applied to mental health and rehabilitation? Psychology ...
Cell and molecular signaling, and transport pathways involved in growth factor control of synaptic development and function
(2015)
Brain derived neurotophic factor (BDNF) and its receptor tropomyosin receptor kinase B (TrkB) signaling has been extensively studied for its roles in the central nervous system (CNS) ranging from cell survival, axonal and ...
Celebrating Twenty Years of the Brazilian Symposium on Cardiovascular Physiology
(2017)
This e-book is dedicated to the celebration of 20 years of the Brazilian Symposium on Cardiovascular Physiology. In 1996 groups from the School of Medicine of Ribeirao Preto, University of Sao Paulo (FMRP-USP) and from the ...
Cerebral endothelial and glial cells are more than bricks in the Great Wall of the brain: Insights into the way the blood-brain barrier actually works (Celebrating the centenary of Goldman's experiments)
(2015)
When Ehrlich discovered the first evidence of the blood-brain barrier in 1885, he probably did not perceive the Great Wall that remained hidden from consciousness inside the central nervous system. Ehrlich had observed ...
Cerebral oxygenation in health and disease
(2015)
Scientists and clinicians interested in cerebrovascular physiology in humans now have numerous possibilities to monitor, invasively or non-invasively, the oxygenation status of cerebral tissue. Monitoring cerebral oxygenation ...
The Cerebellum: From Development to Learning
(2015)
In this book, laboratory leaders on cerebellar neuroscience have revised the present body of knowledge about cerebellum anatomy and function. The trip throughout the cerebellar vineyard organization starts from the causal ...
Biological Engagement Programs: Reducing Threats and Strengthening Global Health Security Through Scientific Collaboration
(2017)
Biological engagement programs are a set of projects or activities between partner countries that strengthen global health security to achieve mutually beneficial outcomes. Engagement programs are an effective way to work ...
Biological Ontologies and Semantic Biology
(2014)
As the amount of biological information and its diversity accumulates massively there is a critical need to facilitate the integration of this data to allow new and unexpected conclusions to be drawn from it. The Semantic ...
Biological Hazards in Food
(2017)
The ingestion of food containing pathogenic microorganisms (i.e. bacteria and their toxins, fungi, viruses) and parasites can cause food-borne diseases in humans. A growing number of emerging pathogens, changes of virulence ...
Biotrophic Plant-Microbe Interactions
(2017)
Throughout their life, plants interact with all sorts of microbes. Some of these are detrimental and cause disease; some interactions are mutually beneficial for both partners. It is clear that most, if not all, of the ...
Biotechnology of Microalgae, Based on Molecular Biology and Biochemistry of Eukaryotic Algae and Cyanobacteria
(2017)
Bioechnology of microalgae takes much attention because of their ability to utilize light energy and fix CO2. Research in biotechnology of microalgae including eukaryotic algae and cyanobacteria is an important and attractive ...
Charophytes: Evolutionary Ancestors of Plants and Emerging Models for Plant Research
(2017)
The charophytes are the group of green algae that are anestral and most closely related to land plants. Today, these organisms are not only important in evoutionary studies but have become outstanding model organisms for ...
Computational Systems Biology of Pathogen-Host Interactions
(2016)
A thorough understanding of pathogenic microorganisms and their interactions with host organisms is crucial to prevent infectious threats due to the fact that Pathogen-Host Interactions (PHIs) have critical roles in ...
Character, Responsibility, and Well-Being: Influences on Mental Health and Constructive Behavior Patterns
(2016)
Character can be defined as self-aware knowledge that helps the individual to set goals, values and ethical principles (Cloninger, 2004). This meta-cognitive dimension of human personality involves ‘Theory of Mind’, and ...
The biology and ecology of ticks shape the potential for the transmission of zoonotic pathogens
(2015)
Ticks are noticeable by the high diversity of pathogens they can transmit, most of them with implications in human and animal health. Ticks are arachnids, meaning that they do not share the biological and ecological features ...
Biology and Pathogenesis of Legionella
(2018)
Legionella pneumophila was first isolated as the causative agent of a deadly infectious pneumonia at a convention of the American Legion forty years ago. Since then, Legionnaires’ disease continues to be a significant ...
Biology of Brain Disorders
(2018)
Brain disorders, including neurological and neuropsychiatric conditions, represent a challenge for public health systems and society at large. The limited knowledge of their biology hampers the development of diagnostic ...
Biosignal processing and computational methods to enhance sensory motor neuroprosthetics
(2016)
Though there have been many developments in sensory/motor prosthetics, they have not yet reached the level of standard and worldwide use like pacemakers and cochlear implants. One challenging issue in motor prosthetics is ...
Breaking the cycle: Attacking the malaria parasite in the liver
(2015)
Despite significant progress in the global fight against malaria, this parasitic infection is still responsible for nearly 300 million clinical cases and more than half a million deaths each year, predominantly in African ...
The Coming of Age of Insulin-Signalling in Insects
(2015)
The new millennium has seen a major paradigm shift in insect endocrinology. Great advancements are being made which establish that nutrition and growth play a central role in diverse cellular and physiological phenomena ...
A comparative survey of the RF-amide peptide superfamily
(2015)
The discovery, twelve years ago, that the RF-amide peptide kisspeptin, acting via GPR54, is essential for the onset of puberty and reproduction, has been a major breakthrough in reproductive physiology. It has also put in ...
Comparative studies between HTLV-1 and HTLV-2 function and pathobiology
(2015)
Human T-cell leukemia viruses type 1 and 2 (HTLV-1 and HTLV-2) share a common genetic organization, expression strategy and ability to infect and immortalize T-cells in vitro; however, HTLV-1 and HTLV-2 are strikingly ...
Comparative Studies of Energy Homeostasis in Vertebrates
(2018)
A brief glimpse into new insight driving the comparative biology of energy homeostasis in vertebrates with a focus on non-mammalian vertebrates. What are the key conserved mechanisms and what aspects of feeding behavior ...
Computational and Experimental Approaches in Multi-Target Pharmacology
(2017)
The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target ...
Control of Visceral Leishmaniasis by Immunotherapeutic and Prophylactic Strategies
(2015)
Visceral leishmaniasis (VL) or kala-azar is the most dreadful of all forms of leishmaniasis caused by Leishmania donovani in Old World and Leishmania chagasi and/or Leishmania infantum in New World affecting millions of ...
Control of Pestivirus Infections in the Management of Wildlife Populations
(2016)
Infections with recognized and putative species of the genus pestivirus are not host-specific and are documented in many wildlife species. The study of pestivirus infections in wildlife species is important both to eradication ...
Crop Traits for Defense against Pests and Disease: Durability, Breakdown and Future Prospects
(2017)
With global populations expected to exceed 9.2 billion by 2050 and available land and water resources devoted to crop production dwindling, we face significant challenges to secure global food security. Only 12 plant species ...
Cross Talk between Lymph Node Lymphatic Endothelial Cells and T Cells in Inflammation and Cancer
(2017)
Lymphocytes constantly survey the lymph nodes in search for potential infection by a pathogen. They enter the afferent lymphatic vessel that serves as a conduit to transport the motile lymphocytes to the draining lymph ...
Current challenges in photosynthesis: From natural to artificial
(2014)
Jules Verne (1828-1905), author of Around the World in Eighty Days (1873) and Journey to the Center of the Earth (1864), wrote in 1875: "I believe that water will one day be used as a fuel, because the hydrogen and oxygen ...
Current Challenges and Future Perspectives on Emerging Bioelectrochemical Technologies
(2016)
The increasing demand for energy worldwide, currently evaluated at 13 terawatts per year, has triggered a surge in research on alternative energy sources more sustainable and environmentally friendly. Bio-catalyzed ...
Current Challenges in Cardiovascular Molecular Diagnostics
(2017)
The field of cardiovascular genetics has tremendously benefited from the recent application of massive parallel sequencing technology also referred to as next generation sequencing (NGS). However, along with the discovery ...
Current Challenges in Modeling Cellular Metabolism
(2016)
Mathematical and computational models play an essential role in understanding the cellular metabolism. They are used as platforms to integrate current knowledge on a biological system and to systematically test and predict ...
Dementia, Frailty and Aging
(2018)
The number of older subjects is rapidly increasingly worldwide. As a consequence, the nature of clinical conditions is also changing. Traditional medicine and models of care have been based on the evaluation and treatment ...
Bioactive Compounds from Microbes
(2017)
Microorganisms have had a long and surprising history. They were “invisible” until invention of microscope in the 17th century. Until that date, although they were extensively (but inconsciously) employed in food preservation, ...
Brain and Art
(2014)
Could we understand, in biological terms, the unique and fantastic capabilities of the human brain to both create and enjoy art? In the past decade neuroscience has made a huge leap in developing experimental techniques ...
Brief Interventions for Risky Drinkers
(2016)
Alcohol is the sixth leading risk factor for disability and premature death all over the world, and one of the leading causes of premature mortality in western societies; it is a leading risk factor for death in young and ...
Bridging the Gap Between Policy and Science in Assessing the Health Status of Marine Ecosystems, 2nd Edition
(2017)
Marine management requires approaches which bring together the best research from the natural and social sciences. It requires stakeholders to be well-informed by science and to work across administrative and geographical ...
Bridging the Theories of Affordances and Limb Apraxia
(2017)
Affordances are meaningful relations between the features of observed objects and the observer's action systems with its proper abilities. The notion of affordance integrates perceptual, cognitive and motor functions, so ...
Children and Companion Animals: Psychosocial, Medical, and Neurobiological Implications
(2018)
Children and companion animals seem to have a natural affinity towards each other. Most children desire a relationship with their own companion animals or at least demonstrate an interest to interact with animals in general. ...
Conflict and Cooperation in Microbial Societies
(2017)
The most evident aspect of biodiversity is the variety of complex forms and behaviors among organisms, both living and extinct. Comparative molecular and physiological studies show that the evolution of complex phenotypic ...
Consciousness and Action Control
(2014)
The basic nuts and bolts underlying human behavior remain mysterious from a scientific point of view. Everyday acts - naming an object, suppressing the urge to say something, or grabbing a waiter’s attention with a ...
Corporate Social Responsibility and Organizational Psychology: Quid pro Quo
(2017)
Researchers, corporate leaders, and other stakeholders have shown increasing interest in Corporate Social Responsibility (CSR)—a company’s discretionary actions and policies that appear to advance societal well-being beyond ...
Creativity and Mental Imagery
(2016)
Creativity is increasingly attracting attention of scientific community given its role in different aspects of human life. So far we have only began to understand its complexity and how it correlates with other cognitive ...