Publications
Now showing items 681-700 of 1372
Molecular mechanisms regulating cytotoxic lymphocyte development and function, and their associations to human diseases
(2015)
Cytotoxic lymphocytes, comprised of NK cells and cytotoxic T cells, play a pivotal role in immune defense. By directed release of perforin-containing lytic granules, NK and cytotoxic T cells can eradicate pathogen-infected, ...
The molecular pathology of cognitive decline: Focus on metals
(2016)
In the past two decades there have been significant advances made in understanding the cellular and molecular alterations that occur with brain ageing, as well as with our understanding of age-related brain diseases. Ageing ...
Molecular Organization of Membranes: Where Biology Meets Biophysics
(2018)
Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed ...
Molecular mechanisms of cellular stress responses in cancer and their therapeutic implications
(2015)
In response to stress, cells can activate a myriad of signalling pathways to bring about a specific cellular outcome, including cell cycle arrest, DNA repair, senescence and apoptosis. This response is pivotal for tumour ...
Molecular mechanisms for reprogramming hippocampal development and function by early-life stress
(2016)
The early postnatal period is a crucial stage for hippocampal development. During this critical period, the neonatal hippocampus is highly sensitive to the detrimental consequences of adverse environmental factors. Extensive ...
Molecular Nanomachines of the Presynaptic Terminal
(2016)
Synaptic transmission is the basis of neuronal communication and is thus the most important element in brain functions, ranging from sensory input to information processing. Changes in synaptic transmission can result in ...
Molecular Pathogenesis of Pneumococcus
(2017)
Streptococcus pneumoniae has been for decades the number one bacterial killer of children in the world. Although vaccination with pneumococcal vaccines [PCV7, PCV10, and PCV13 (children) or PPSV23 (adults)] has helped ...
NETosis 2: The Excitement Continues
(2017)
NETosis, a form of cell death that manifests by the release of decondensed chromatin to the extracellular space, provides valuable insights into mechanisms and consequences of cellular demise. Because extracellular chromatin ...
Neuro-motor control and feed-forward models of locomotion in humans
(2015)
Locomotion involves many different muscles and the need of controlling several degrees of freedom. Despite the Central Nervous System can finely control the contraction of individual muscles, emerging evidences indicate ...
Neuro-Immune Interactions in Inflammation and Autoimmunity
(2018)
The nervous system plays an important role in the regulation of immunity and inflammation. On the other hand unbalanced immune responses in inflammatory and autoimmune conditions may have a deleterious impact on neuronal ...
Neuro-Education and Neuro-Rehabilitation
(2016)
In the last decade, important discoveries have been made in cognitive neuroscience regarding brain plasticity and learning such as the mirror neurons system and the anatomo-functional organization of perceptual, cognitive ...
Nature and Environment: The Psychology of Its Benefits and Its Protection
(2017)
Our Research Topic section entitled: "Nature and the environment: The psychology of its benefits and its protection" will have two main lines. The first line of articles will center upon cutting-edge research showing how ...
Neuropsychopharmacology of Psychosis: Relation of Brain Signals, Cognition and Chemistry
(2015)
Previous research over the past decades has identified diverse neurobiological underpinnings of psychosis. In particular, by combining a variety of different neuroimaging modalities, it has been shown that psychotic states ...
Neuroplasticity and Extracellular Proteolysis
(2016)
Neuroplasticity refers to the ability of the Central Nervous System (CNS) to alter its structure and function in response to a variety of physiological and pathological processes such as development, cognition, injury or ...
Neuroscience perspectives on Security: Technology, Detection, and Decision Making
(2015)
In security science, efficient operation depends typically on the interaction between technology, human and machine detection and human and machine decision making. A perfect example of this interplay is ‘gatekeeping’, ...
Neuroplasticity and Neurorehabilitation
(2015)
In the history of neuroscience it had long been a virtually axiomatic belief that the mature mammalian nervous system was hardwired and fixed. This view goes back to the work of Louis Broca in the 1850s and has been perhaps ...
Neuroscience of Human Attachment
(2017)
Attachment is a biologically emotion regulation based system guiding cognitive and emotional processes with respect to intimate and significant relationships. Secure relationships promote infants’ exploration of the world ...
Neuropsychology and Neuropsychiatry of Neurodegenerative Disorders
(2016)
This book compiles all articles within the Research Topic "Neuropsychology and neuropsychiatry of neurodegenerative disorders" published in the journal Frontiers in Aging Neuroscience. The call was launched in 2014 and ...
Mental Practice - Clinical and Experimental Research in Imagery and Action Observation
(2016)
There is now strong evidence demonstrating that the brain simulates action and other functions. Such action simulation can be evoked through conscious mental rehearsal of movement or imagery, but also through passive action ...
The metabolic challenges of immune cells in health and disease
(2015)
Obesity and its co-morbidities, including atherosclerosis, insulin resistance and diabetes, are a world-wide epidemic. Inflammatory immune responses in metabolic tissues have emerged as a universal feature of these metabolic ...