Publications
Now showing items 901-920 of 1372
The Physiological Functions of the Amyloid Precursor Protein Gene Family
(2017)
The amyloid precursor protein APP plays a key role in the pathogenesis of Alzheimer’s disease (AD), as proteolytical cleavage of APP gives rise to the Aß peptide which is deposited in the brains of Alzheimer patients. ...
Physiological and molecular ecology of aquatic cyanobacteria
(2015)
The cyanobacteria inhabit every illuminated environment on Earth, from polar lakes to desert crusts and through their phototrophic metabolism play essential roles in global geochemical cycles. With the discovery of marine ...
Physiological Adaptations to Swimming in Fish
(2017)
Swimming is an integral part of the life history of many fish species as is intimately linked with their ability to express feeding and predator avoidance behaviors, habitat selection and environmental preferences, social ...
Planctomycetes-Verrucomicrobia-Chlamydiae Bacterial Superphylum: New Model Organisms for Evolutionary Cell Biology
(2017)
The Planctomycetes, Verrucomicrobia, Chlamydiae (PVC) and related phyla have recently emerged as fascinating subjects for research in evolutionary cell biology, ecology, biotechnology, evolution and human health. This ...
New edge of antibiotic development: antimicrobial peptides and corresponding resistance
(2014)
Antimicrobial peptides, commonly isolated from several organisms, have been considered part of innate immune system and also as potential antimicrobial drugs. Besides its antimicrobial activity, some AMPs also have antifungal ...
New Trends on Genome and Transcriptome Characterizations
(2018)
This Research Topic is devoted to bioinformaticians, geneticists and researchers who study or apply methods and algorithms for genomes and transcriptome analyses, aimed at understanding pathology discriminations and ...
Mathematical and Statistics Anxiety: Educational, Social, Developmental and Cognitive Perspectives
(2017)
Mathematical anxiety is a feeling of tension, apprehension or fear which arises when a person is faced with mathematical content. The negative consequences of mathematical anxiety are well-documented. Students with high ...
Platelets as immune cells in physiology and immunopathology
(2015)
Are platelets cells? (Not everyone agrees, since they are non-nucleate). And if platelets are cells - which all specialists consider at the time being - are they immune cells? The issue that platelets participate in immunity ...
Plastid Proteostasis: Relevance of Transcription; Translation and Post-Translational Modifications
(2017)
Due to their bacterial endosymbiotic origin plastids are organelles with both nuclear-encoded and plastid-encoded proteins. Therefore, a highly integrated modulation of gene expression between the nucleus and the plastome ...
Plasticity of primary afferent neurons and sensory processing after spinal cord injury
(2015)
Traumatic injury of the spinal cord affects the entire organism directly and indirectly. Primary injury destroys neurons and severs axons which participate in neural circuits. Secondary injuries and pathologies arise from ...
Plasticity of GABAergic synapses
(2016)
Learning and memory are believed to depend on plastic changes of neuronal circuits due to activity-dependent potentiation or depression of specific synapses. During the last two decades, plasticity of brain circuits was ...
Optical Approaches to Capture Plant Dynamics in Time, Space, and Across Scales
(2018)
Quantifying temporal changes in plant geometry as a result of genetic, developmental, or environmental causes is essential to improve our understanding of the structure and function relationships in plants. Over the last ...
The oral microbiome in an ecological perspective
(2015)
The oral cavity harbors an immense diversity of microorganisms, including bacteria, fungi, archaea, protozoa and viruses. At health, oral microbial community is thought to be in a state of homeostasis, even after numerous ...
Perceiving and Acting in the Real World: From Neural Activity to Behavior
(2016)
One remarkable ability of the human brain is to process large amounts of information about our surroundings to allow us to interact effectively with them. In everyday life, the most common way to interact with objects is ...
Perception of visual advertising in different media: from attention to distraction, persuasion, preference and memory
(2015)
This Research Topic aims to showcase the state of the art in visual advertising research. Although visual processes are a central component of consumer behavior, they have been largely neglected in models explaining consumer ...
Perception and Cognition: Interactions in the Ageing Brain
(2016)
Healthy ageing can lead to declines in both perceptual and cognitive functions. Impaired perception, such as that resulting from hearing loss or reduced visual or tactile resolution, increases demands on ‘higher-level’ ...
Personalized Medicine and Neurosurgery
(2017)
The Precision Medicine Initiative, which was instituted by President Barack Obama on January 20, 2015, highlighted the importance that advances in genomics and related “-omic” approaches have made to science and medicine, ...
Origin and spatiotemporal dynamics of the peroxisomal endomembrane system
(2015)
The peroxisome is an organelle with essential roles in lipid metabolism, maintenance of reactive oxygen species homeostasis, and anaplerotic replenishment of tricarboxylic acid cycle intermediates destined for mitochondria. ...
The Origin of the Plasma Cell Heterogeneity
(2015)
Plasma cells (PCs) are terminally differentiated B-cells producing large amounts of immunoglobulins (Ig). In humans, most of circulating Ig are produced by bone marrow plasma cells. PCs differentiate from activated naïve ...
Paradigm changes are required in HIV vaccine research
(2015)
In his 1962 book "The Structure of Scientific Revolutions", Thomas Kuhn famously argued that researchers in every field of scientific enquiry always operate under a set of presuppositions known as paradigms that are rarely ...