Publications
Now showing items 921-940 of 1372
Podocyte Pathology and Nephropathy
(2015)
The understanding of the pathogenesis of diabetic nephropathy (DN) has advanced considerably in the last few years. Much has been learned about the natural history, the relative lack of significance of microalbuminuria in ...
Phonology in the Bilingual and Bidialectal Lexicon
(2017)
A conversation between two people can only take place if the words intended by each speaker are successfully recognized. Spoken word recognition is at the heart of language comprehension. This automatic and smooth process ...
Phonological and phonetic competence: between grammar, signal processing, and neural activity
(2016)
The present collection of articles brings together experimental work in the field of segmental and prosodic processing and representation in phonology and phonetics. Contributions focus on the exploration of human cognitive, ...
PI3K signalling
(2015)
The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role ...
New Frontiers in Multiscale Modelling of Advanced Materials
(2016)
Atomistic simulations, based on ab-initio and semi-empirical approaches, are nowadays widespread in many areas of physics, chemistry and, more recently, biology. Improved algorithms and increased computational power widened ...
New frontiers in the neuropsychopharmacology of mental illness
(2015)
In recent years, mental illnesses have become recognized as a huge emotional and financial burden to the individual, their relatives and society at large. Stress-related and mood disorders as well as psychoactive substance ...
Novel Therapeutic Targets and Emerging Treatments for Fibrosis
(2018)
For decades we have known that the overgrowth, hardening and scarring of tissues (so-called fibrosis) represents the final common pathway and best histological predictor of disease progression in most organs. Fibrosis is ...
Novel roles of non-coding brain RNAs in health and disease
(2014)
Non-coding RNAs (ncRNAs), and in particular microRNAs are rapidly becoming the focus of research interest in numerous basic and translational fields, including brain research; and their importance for many aspects in brain ...
Measurement Invariance
(2015)
Multi-item surveys are frequently used to study scores on latent factors, like human values, attitudes and behavior. Such studies often include a comparison, between specific groups of individuals, either at one or multiple ...
Open questions on the mechanisms of neuromodulation with applied and endogenous electric fields
(2015)
Despite increased knowledge, and more sophisticated experimental and modeling approaches, fundamental questions remain about how electricity can interact with ongoing brain function in information processing or as a medical ...
Organic Ligands in Marine Trace Metal Biogeochemistry
(2018)
This research topic highlights the most recent accomplishments of a Scientific Committee on Oceanic Research (SCOR) Working Group, SCOR WG 139: Organic Ligands - A Key Control on Trace Metal Biogeochemistry in the Ocean.
Nucleation and Crystallization of Glasses and Glass-Ceramics
(2017)
The E-book "Nucleation and Crystallization of Glasses and Glass-Ceramics" highlights historic perspectives and current research in the field of glass-ceramic technology. Glass-ceramic technology is promising to provide us ...
The origin, function and diagnostic potential of extracellular microRNA in human body fluids
(2014)
Short non-coding RNA molecules, microRNAs (miRNAs), post-transcriptionally regulate gene expression in living cells. In recent years, miRNAs have been found in a wide spectrum of mammalian body fluids including blood plasma, ...
Origin of Tropical Diversity: From Clades to Communities
(2017)
In this volume we aimed to assess progress in determining the processes by which current patterns of tropical biodiversity were established and are maintained. Tropical regions are highly species-rich and we present studies ...
The Parallel March of Asthma and Allergy in Childhood: A Multi-Perspective Approach
(2018)
It has not been yet clarified whether allergy and asthma are part of the same condition or they follow a parallel path. This Research Topic aims to try and put some light in this parallel march going through crucial topics: ...
Pathogenic Advances and Therapeutic Perspectives for Eosinophilic Inflammation
(2018)
With the recent approval of the first eosinophil-depleting therapeutic agents targeting the IL-5 pathway for treatment of severe eosinophilic asthma, eosinophils and eosinophilic disorders are in the limelight. Indeed, ...
The pathogenic Yersiniae - advances in the understanding of physiology and virulence
(2014)
For decades, pathogenic Yersinia have served as an inventive model organism for researchers seeking to understand the complexities of bacteria-host cell interactions. In fact, seminal studies on Yersinia virulence mechanisms ...
The Pathogenetic Mechanisms at the Basis of Aortopathy Associated with Bicuspid Aortic Valve: Insights from "Omics", Models of Disease and Emergent Technologies
(2018)
This forum of comprehensive reviews and research studies on distinct aspects of the pathophysiology of BAV aortopathy provides both the state of the art in the knowledge on this complex disease and novel insights into its ...
Pathologic Conditions of the Human Nervous and Muscular Systems Associated with Mutant Chaperones: Molecular and Mechanistic Aspects
(2018)
This eBook presents illustrative examples of genetic chaperonopathies affecting primarily nerves and muscles and discusses molecular mechanisms and treatment targeting chaperones, i.e., chaperonotherapy.
Pathogenesis of Leptospira
(2018)
The present eBook, consisting of a compilation of research and review articles, focuses on the features and mechanisms adopted and explored by pathogenic leptospires to successfully establish infection in the host. ...