Publications
Now showing items 481-490 of 1372
Homeostatic and retrograde signaling mechanisms modulating presynaptic function and plasticity
(2016)
Activity within neural circuits shapes the synaptic properties of component neurons in a manner that maintains stable excitatory drive, a process referred to as homeostatic plasticity. These potent and adaptive mechanisms ...
Host-adapted metabolism and its regulation in Bacterial Pathogens
(2015)
Pathogens adapt their metabolism rapidly to the host. Our topic covers these phenomenon regarding extracellular and intracellular pathogens as well as general methods to elucidate different metabolic adaptation processes ...
How Humans Recognize Objects: Segmentation, Categorization and Individual Identification
(2016)
Human beings experience a world of objects: bounded entities that occupy space and persist through time. Our actions are directed toward objects, and our language describes objects. We categorize objects into kinds that ...
How nature shaped echolocation in animals
(2014)
Echolocation has evolved in different groups of animals, from bats and cetaceans to birds and humans, and enables localization and tracking of objects in a dynamic environment, where light levels may be very low or absent. ...
How Salmonella infection can inform on mechanisms of immune function and homeostasis
(2016)
The use of model antigens such as haptens and ovalbumin has provided enormous insights into how immune responses develop, particularly to vaccine antigens. Furthermore, these studies are overwhelmingly performed in animals ...
How Fear and Stress Shape the Mind
(2016)
The experience of fear and stress leaves an indelible trace on the brain. This indelible trace is observed as both changes in behavior and changes in neuronal structure and function. Fear and stress interact on many levels. ...
Hypoxia in Kidney Disease
(2018)
Kidney disease is a complex health problem, often coinciding with cardiovascular pathology (e.g. hypertension) and metabolic disturbances (e.g. obesity and diabetes). It is also a disturbingly fast growing global public ...
ICT for assessment and rehabilitation in Alzheimer's disease and related disorders
(2016)
Information and Communication Technologies (ICT) are no longer objects gathering dust on a shelf; instead, they have become intrinsic in our everyday lives. They are now even taking on an indispensable role in many clinical ...
Immune Checkpoint Molecules and Cancer Immunotherapy
(2019)
For the faultless function of the immune system, tight regulation of immune cell activation, immuno-suppression and the strength and efficiency of the immune response is essential. Immune checkpoint (ICP) molecules can ...
Immune Interactions during the Reproductive Cycle
(2015)
Mammalian pregnancy represents a unique immunological riddle in that the mother does not reject her allogeneic fetus. In part this is largely due to a general sequestration or diminution of T cell activity, and an increased ...