Publications
Now showing items 161-200 of 1372
Crosstalk between the osteogenic and neurogenic stem cell niches: how far are they from each other?
(2016)
Somatic stem cells reside in definite compartments, known as “niches”, within developed organs and tissues, being able to renew themselves, differentiate and ensure tissue maintenance and repair. In contrast with the ...
Bioinformatics of Non-Coding RNAs with Applications to Biomedicine: Recent Advances and Open Challenges
(2017)
The recent discovery of small and long non-coding RNAs (ncRNAs) has represented a major breakthrough in the life sciences. These molecules add a new layer of complexity to biological processes and pathways by revealing a ...
Bone Marrow Adipose Tissue: Formation; Function; and Impact on Health and Disease
(2017)
Adipocytes are a major component of the bone marrow, accounting for up to 70% of total bone marrow volume in healthy humans. Indeed, this bone marrow adipose tissue (often referred to as ‘MAT’ or ‘BMAT’) accounts for at ...
Bone Marrow T Cells at the Center Stage in Immunological Memory
(2017)
Increasing evidence supports the notion that bone marrow (BM) represents a relevant player in T cell responses, particularly in its role as a specialized organ for long-term memory. Memory T cells are enriched in the BM ...
The Brassicaceae Agri-Horticultural and Environmental Perspectives
(2018)
This Frontiers Research Topic "The Brassicaceae- Agri-Horticultural and Environmental Perspectives" is an effort to provide a common platform to agronomists, horticulturists, plant breeders, plant geneticists/molecular ...
Computational Methods for Understanding Complexity: The Use of Formal Methods in Biology
(2016)
The complexity of living organisms surpasses our unaided habilities of analysis. Hence, computational and mathematical methods are necessary for increasing our understanding of biological systems. At the same time, there ...
Building the gateway to consciousness - about the development of the thalamus
(2015)
Since years, patterning and function of some brain parts such as the cortex in the forebrain and the optical tectum or cerebellum in the midbrain/hindbrain region are under strong investigation. Interestingly the diencephalon ...
Cortico-cortical Communication Dynamics
(2014)
Neurons communicate by sending action potentials down their axons and release neurotransmitter at the synapses with target neurons in nearby or remote regions. Although we know the approximate connectivity of cortico-cortical ...
Critical Earthquake Response of Elastic-Plastic Structures Under Near-Fault Ground Motions: Closed-Form Approach via Impulse Input
(2016)
The specialty section Earthquake Engineering is one branch of Frontiers in Built Environment and welcomes critical and in-depth submissions on earthquake ground motions and their effects on buildings and infrastructures. ...
Criticality as a signature of healthy neural systems: multi-scale experimental and computational studies
(2015)
Since 2003, when spontaneous activity in cortical slices was first found to follow scale-free statistical distributions in size and duration, increasing experimental evidences and theoretical models have been reported in ...
Critical Earthquake Response of Elastic-Plastic Structures and Rigid Blocks under Near-Fault Ground Motions: Closed-Form Approach via Double Impulse
(2016)
This eBook is the second in a series of books on the critical earthquake response of elastic-plastic structures or rigid blocks under near-fault ground motions, and includes four original research papers which were published ...
Continuous Quality Improvement - Advancing Understanding of Design, Application, Impact and Evaluation of CQI Approaches
(2017)
Continuous Quality Improvement (CQI) methods are increasingly widely used to bridge the gaps between the evidence base for best clinical practice, what actually happens in practice, and the achievement of better population ...
Biofilms from a Food Microbiology Perspective: Structures, Functions and Control Strategies
(2017)
Materials and equipment in food processing industries are colonized by surface-associated microbial communities called biofilms. In these biostructures microorganisms are embedded in a complex organic matrix composed ...
Biofilm formation by staphylococci and streptococci: Structural, functional and regulatory aspects and implications for pathogenesis
(2015)
Members of the genus Staphylococcus and Streptococcus are the causative agnets of many human and animal diseases. Over the past decade the complete sequencing of many staphylococcal and streptococcal genomes has promoted ...
Biomaterials and Bioactive Molecules to Drive Differentiation in Striated Muscle Tissue Engineering
(2016)
Tissue engineering is an innovative, multidisciplinary approach which combines (bio)materials, cells and growth factors with the aim to obtain neo-organogenesis to repair or replenish damaged tissues and organs. The ...
Branching and Rooting Out with a CT Scanner: The Why, the How, and the Outcomes, Present and Possibly Future
(2016)
Until recently, a majority of the applications of X-ray computed tomography (CT) scanning in plant sciences remained descriptive; some included a quantification of the plant materials when the root-soil isolation or ...
Brain-Mind-Body Practice and Health
(2018)
It is acknowledged that practice could induce rapid change or reorganization of the brain’s cellular or neural networks as well as behaviors. Notably, practice relevant to mental or physical approach attracted great attention ...
Brain-immune interactions in health and disease
(2015)
Brain-immune interactions are essential to maintain health and their dysfunction contributes to diverse human diseases. Recent data show that haematopoietic processes and immune organs are under central autonomic control. ...
A Broader View for Plant EvoDevo: Novel Approaches for Diverse Model Systems
(2017)
This collection attempts to integrate work pertaining to a fundamental question in plant evolution: What are the molecular underpinnings for the origin of different plant forms? Among the many facets this question touches ...
Chemicals in the Environment and Brain Development: Importance of Neuroendocrinological Approaches
(2017)
Mounting evidence shows that increasing numbers of children are being diagnosed with neurodevelopmental disorders, and it is clear that this increase cannot be explained by genetic background alone. A number of studies, ...
Comprehensive Systems Biomedicine
(2014)
Systems Biomedicine is a field in perpetual development. By definition a translational discipline, it emphasizes the role of quantitative systems approaches in biomedicine and aims to offer solutions to many emerging ...
Conceptual Categories and the Structure of Reality: Theoretical and Empirical Approaches
(2019)
In this eBook, Conceptual Categories and the Structure of Reality, the title very well describes the book's content. Within the book's pages a selection of academics from a variety of human behaviour, human/social science ...
Correlated neuronal activity and its relationship to coding, dynamics and network architecture
(2014)
Correlated activity in populations of neurons has been observed in many brain regions and plays a central role in cortical coding, attention, and network dynamics. Accurately quantifying neuronal correlations presents ...
Danger Signals Triggering Immune Response and Inflammation
(2017)
The immune system detects "danger" through a series of what we call pathogen-associated molecular patterns (PAMPs) or damage-associated molecular pattern molecules (DAMPs), working in concert with both positive and negative ...
Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges
(2016)
Recent advances in the understanding of the biological basis of pediatric soft-tissue and bone tumors, especially owing to the advent of “omics” technologies, have led to an exponential increase in the current knowledge ...
Biomarkers in Drug Hypersensitivity
(2017)
Biomarkers, especially those based on pharmacogenomics testing, have proved to be extremely useful for type A adverse drug reactions. Clinical practice guidelines based on biomarker testing are presently being developed ...
Biology of Cognitive Aging: Model Systems, Technologies and Beyond
(2017)
Welcome! We, humans, tend to experience forgetfulness when we get old. The forgetfulness may become more serious memory impairment, dementia. Presumably, we have known it for a long time, but we still do not know the ...
Biomarkers of Alzheimer's Disease: The Present and the Future
(2016)
Alzheimer disease (AD) is a neurodegenerative disorder characterized by significant cognitive deficits, behavioral changes, sleep disorders and loss of functional autonomy. AD represents the main cause of dementia and has ...
BK Channels: Integrators of Cellular Signals in Health and Disease
(2017)
Maxi calcium-activated potassium channels (BK) are an amazing category of ion channels which are found in cellular plasma membranes as well as in membranes of intracellular organelles. The function of these channels is to ...
Building Strategies for Porcine Cancer Models
(2018)
The eBook "Building Strategies for Porcine Cancer Models" presents a series of articles demonstrating the state-of-the-art developments in pig models for cancer research. Renowned researchers dedicated to the reproduction, ...
Complex Problem Solving Beyond the Psychometric Approach
(2018)
Complex problem solving (CPS) and related topics such as dynamic decision-making (DDM) and complex dynamic control (CDC) represent multifaceted psychological phenomena. In abroad sense, CPS encompasses learning, decision-making, ...
Controversies and Perspectives in the Use of Postoperative Radiotherapy for Prostate Cancer
(2018)
The use of radical prostatectomy in patients with high risk of recurrence has significantly increased during the past 10 years. Thus, adjuvant radiation as a part of multimodality treatment or salvage radiation at the ...
Controversies in the Local Management of Lung Cancer
(2018)
This special edition of Frontiers in Oncology reviews the current efficacy and limitations of surgical and radiotherapeutic management of lung cancer and provides insight into how local management options may change in the future.
Context in Communication: A Cognitive View
(2017)
Context is what contributes to interpret a communicative act beyond the spoken words. It provides information essential to clarify the intentions of a speaker, and thus to identify the actual meaning of an utterance. A ...
Data-Based Radiation Oncology - Design of Clinical Trials
(2018)
In radiation oncology as in many other specialties clinical trials are essential to investigate new therapy approaches. Usually, preparation for a prospective clinical trial is extremely time consuming until ethics approval ...
Deep Subsurface Microbiology
(2015)
Deep subsurface microbiology is a highly active and rapidly advancing research field at the interface of microbiology and the geosciences; it focuses on the detection, identification, quantification, cultivation and activity ...
Deep Carbon in Earth: Early Career Scientist Contributions to the Deep Carbon Observatory
(2017)
Since its inception, the Deep Carbon Observatory (DCO) has coalesced a multidisciplinary and international group of researchers focused on understanding and quantifying Earth’s deep carbon budget. Carbon is the fourth most ...
Biogenesis of the oxidative phosphorylation machinery in plants. From gene expression to complex assembly
(2014)
Mitochondrial biogenesis is an extremely complex process. A hint of this complexity is clearly indicated by the many steps and factors required to assemble the respiratory complexes involved in oxidative phosphorylation. ...
Biogenic Amines and Neuromodulation of Animal Behavior, 2nd Edition
(2018)
Since Erspamer and Boretti, 1951 first described the biogenic amine octopamine in the octopus salivary gland as a molecule with “adrenaline-like” action, decades of extensive studies demonstrated the important role octopamine ...
Biogenic amines in fermented foods
(2015)
Biogenic amines (BA) are sources of nitrogen and precursors for synthesis of hormones, alkaloids, nucleic acids and proteins, occurring in all organisms. Under normal condition in humans the consumption of food or beverages ...