Publications
Now showing items 531-540 of 1372
Inhibitory Function in Auditory Processing
(2015)
There seems little doubt that from the earliest evolutionary beginnings, inhibition has been a fundamental feature of neuronal circuits - even the simplest life forms sense and interact with their environment, orienting ...
Inhibiting PARP as a Strategic Target in Cancer
(2016)
Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant ...
How and Why Does Spatial-Hearing Ability Differ among Listeners? What Is the Role of Learning and Multisensory Interactions?
(2016)
Spatial-hearing ability has been found to vary widely across listeners. A survey of the existing auditory-space perception literature suggests that three main types of factors may account for this variability: - physical ...
How aging affects T lymphocyte-mediated immunity
(2015)
Increasing age has been associated with an insufficient protection following vaccination and an increased incidence and severity of infectious diseases. The predicted acceleration of global population aging will accentuate ...
The HSP70 Molecular Chaperone Machines
(2017)
Members of the HSP70 family form a central hub of the molecular chaperone network, controlling protein homeostasis in prokaryotes and in the ATP-containing compartments of the eukaryotic cells. The heat-inducible form ...
How to improve immune reconstitution in allogeneic hematopoietic stem cell transplantation?
(2015)
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) is widely used in the treatment of haematological malignancies as a form of immunotherapy acting through a graft-versus-leukemia (GvL) reaction. This curative ...
HSPs - Ambiguous Mediators of Immunity
(2017)
Heat shock proteins (HSPs) were discovered as polypeptides induced by stress that can be found in all kingdoms of cellular organisms. Their functions were, a first enigmatic and these proteins were thus classified by ...
Hybrid Solutions for the Modelling of Complex Environmental Systems
(2017)
Systems studied in environmental science, due to their structure and the heterogeneity of the entities composing them, often exhibit complex dynamics that can only be captured by hybrid modeling approaches. While several ...
Abiotic Stresses in Agroecology: A Challenge for Whole Plant Physiology
(2017)
Understanding plant responses to abiotic stresses is central to our ability to predict the impact of global change and environmental pollution on the production of food, feed and forestry. Besides increasing carbon dioxide ...