Publications
Now showing items 1081-1100 of 1372
Regulatory RNAs in the Nervous System
(2015)
Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these ...
Regulatory potential of post-translational modifications in bacteria
(2015)
Post-translational modifications (PTMs) are widely employed by all living organisms to control the enzymatic activity, localization or stability of proteins on a much shorter time scale than the transcriptional control. ...
Remodeling of cardiac passive electrical properties and susceptibility to ventricular and atrial arrhythmias
(2015)
The effective management of cardiac arrhythmias, either of atrial or of ventricular origin, remains a major challenge. Sudden cardiac death due to ventricular tachyarrhythmias remains the leading cause of death in ...
The Schistosomiasis Vaccine - It Is Time to Stand Up
(2015)
Schistosomiasis is a severe parasitic disease, endemic in 74 developing countries with up to 600 million people, including many children, infected and 800 million at risk of contracting the disease following infection with ...
Schizophrenia: A Consequence of Gene-Environment Interactions?
(2015)
Schizophrenia is a multi-factorial disease characterized by a high heritability and environmental risk factors (e.g. stress and cannabis use). In recent years, an increasing number of researchers worldwide have started ...
Secretion of Cytokines and Chemokines by Innate Immune Cells
(2015)
The release of cytokines, chemokines, and other immune-modulating mediators released from innate immune cells, including eosinophils, neutrophils, macrophages, dendritic cells, mast cells, and epithelial cells, is an ...
Recent advances in γδ T cell biology: New ligands, new functions, and new translational perspectives
(2016)
Gamma/delta (γδ) T-cells are a small subset of T-lymphocytes in the peripheral circulation but constitute a major T-cell population at other anatomical localizations such as the epithelial tissues. In contrast to conventional ...
Recent Advances of Epigenetics in Crop Biotechnology
(2016)
Epigenetics is a new field that explains gene expression at the chromatin structure and organization level. Three principal epigenetic mechanisms are known and hundreds of combinations among them can develop different ...
Recent Advances in the Study of the Host-Fungus Interaction
(2017)
Fungal infections represent nowadays a significant burden on the healthcare system of most of the countries, and are among the infections with the highest mortality rates. This has fostered the study of the interaction of ...
Retroviruses, retroelements and their restrictions
(2015)
Human retroviruses, HIV and HTLV have been recognized as important pathogens because of their association with lethal diseases such as AIDS and ATL. Considerable resources and efforts have been directed at understanding ...
Risk Factors for Pancreatic Cancer: Underlying Mechanisms and Potential Targets
(2015)
Pancreatic Cancer has been and still is one of the deadliest types of human malignancies. The annual mortality rates almost equal incidence rates making this disease virtually universally fatal. The 5-year survival of ...
Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function, 2nd Edition
(2018)
Genetic variations may change the structure and function of individual proteins as well as affect their interactions with other proteins and thereby impact metabolic processes dependent on protein-protein interactions. For ...
Role of Silicon in Plants
(2017)
Silicon (Si) is gaining increased attention in the farming sector because of its beneficial effects observed in several crop species, particularly under stress conditions. The magnitude of benefits is predominantly observed ...
Role of Protein-Protein Interactions in Metabolism: Genetics, Structure, Function
(2018)
Genetic variations may change the structure and function of individual proteins as well as affect their interactions with other proteins and thereby impact metabolic processes dependent on protein-protein interactions. For ...
The Role of Primary Motor Cortex as a Marker for and Modulator of Pain Control and Emotional-Affective Processing
(2017)
The sensory and motor cortical homunculi proposed by Walter Penfield were a major landmark for the anatomical mapping of the brain. More than 60 years after, the development of new tools to investigate brain function ...
The Role of Play in Child Assessment and Intervention
(2017)
Play is a ubiquitous and universal aspect of early childhood. Although it may take different forms throughout development and across cultures, decades of research have found play to be related to important, positive outcomes. ...
The regulation of angiogenesis by tissue cell-macrophage interactions
(2014)
Angiogenesis is the physiological process where new blood vessels grow from existing ones, in order to replenish tissues suffering from inadequate blood supply. Perhaps the most studied angiogenic process occurs in solid ...
Regulation and targeting of enzymes mediating Parkinson's disease pathogenesis: focus on Parkinson's disease Kinases, GTPases and ATPases
(2015)
Understanding the molecular pathogenesis of Parkinson’s disease (PD) is a priority in biomedical research and a pre-requisite to improve early disease diagnosis and ultimately to developing disease-modifying strategies. ...
Regulation of Cell Fate Determination in Plants
(2014)
Plants are made up of a large number of distinct cell types that originate from a single fertilized egg cell. How the diversity of cell types arise in appropriate places is one of the most fascinating and attractive research ...
The regulated secretory pathway in neuroendocrine cells
(2014)
The regulated secretory pathway is a hallmark of neuroendocrine cells. This process comprises many sequential steps, which include ER-associated protein synthesis, post-translational modification of proteins in the Golgi ...