Show simple item record

Advances in Mechanisms of Renal Fibrosis

dc.contributor.authorDavid J. Nikolic-Paterson*
dc.contributor.authorHui Y. Lan*
dc.date.accessioned2021-02-11T07:49:19Z
dc.date.available2021-02-11T07:49:19Z
dc.date.issued2018*
dc.date.submitted2019-01-23 14:53:42*
dc.identifier31910*
dc.identifier.issn16648714*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/40307
dc.description.abstractScarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive update on TGF-β signalling pathways and introduces a range of cellular and molecular mechanisms involved in renal fibrosis both upstream and downstream of TGF-β. The wide variety of potential new targets described herein bodes well for the future development of effective therapies to tackle the major clinical problem of progressive renal fibrosis.*
dc.languageEnglish*
dc.relation.ispartofseriesFrontiers Research Topics*
dc.subjectQP1-981*
dc.subjectQ1-390*
dc.subject.classificationthema EDItEUR::M Medicine and Nursing::MF Pre-clinical medicine: basic sciences::MFG Physiologyen_US
dc.subject.otherTGF-beta*
dc.subject.otherfibroblast*
dc.subject.otherJNK*
dc.subject.othermiRNA*
dc.subject.otherSmad*
dc.subject.othernon-classical RAS*
dc.subject.otherBMP7*
dc.subject.otherHDAC*
dc.subject.otherHIPK2*
dc.titleAdvances in Mechanisms of Renal Fibrosis*
dc.typebook
oapen.identifier.doi10.3389/978-2-88945-499-0*
oapen.relation.isPublishedBybf5ce210-e72e-4860-ba9b-c305640ff3ae*
oapen.relation.isbn9782889454990*
oapen.pages84*


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

https://creativecommons.org/licenses/by/4.0/
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by/4.0/