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AMP-Activated Protein Kinase Signalling

dc.contributor.authorNeumann, Dietbert*
dc.contributor.authorViollet, Benoit*
dc.date.accessioned2021-02-11T08:09:00Z
dc.date.available2021-02-11T08:09:00Z
dc.date.issued2019*
dc.date.submitted2019-03-21 14:08:22*
dc.identifier32588*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/40775
dc.description.abstractStarting from a kinase of interest, AMP-activated protein kinase (AMPK) has gone far beyond an average biomolecule. Being expressed in all mammalian cell types and probably having a counterpart in every eukaryotic cell, AMPK has attracted interest in virtually all areas of biological research. Structural and biophysical insights have greatly contributed to a molecular understanding of this kinase. From good old protein biochemistry to modern approaches, such as systems biology and advanced microscopy, all disciplines have provided important information. Thus, multiple links to cellular events and subcellular localizations have been established. Moreover, the crucial involvement of AMPK in human health and disease has been evidenced. AMPK accordingly has moved from an interesting enzyme to a pharmacological target. However, despite our extensive current knowledge about AMPK, the growing community is busier than ever. This book provides a snapshot of recent and current AMPK research with an emphasis on work providing molecular insight, including but not limited to novel physiological and pathological functions, or regulatory mechanisms. Up-to-date reviews and research articles are included.*
dc.languageEnglish*
dc.subjectQH301-705.5*
dc.subjectQ1-390*
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.othern/a*
dc.subject.otherHDACs*
dc.subject.othertranscription*
dc.subject.otherepigenetics*
dc.subject.otherspermatozoa*
dc.subject.otherpar complex*
dc.subject.otherA769662*
dc.subject.otherMDCK*
dc.subject.otherskeletal muscle*
dc.subject.otherAID*
dc.subject.otherphosphorylation*
dc.subject.otherenergy metabolism*
dc.subject.othermonocytes*
dc.subject.otherautophagy*
dc.subject.otherCML*
dc.subject.otherliver*
dc.subject.otherhindlimb suspension*
dc.subject.otherpregnancy*
dc.subject.otherpreeclampsia*
dc.subject.othergestational diabetes mellitus*
dc.subject.otherCaMKK2*
dc.subject.otherassisted reproduction techniques*
dc.subject.othernutrient-sensing signals*
dc.subject.othersonic hedgehog*
dc.subject.otherprotein acetylation*
dc.subject.otherglycogen storage disease*
dc.subject.otherAMPK*
dc.subject.otheradenosine monophosphate-activated protein kinase*
dc.subject.otherAICAR*
dc.subject.otherindirect calorimetry*
dc.subject.otherIL-1?*
dc.subject.otherMyHC I(?)*
dc.subject.otherHDAC4/5*
dc.subject.otherendothelial cells*
dc.subject.otherinfection*
dc.subject.otherhepatocyte*
dc.subject.otherp70S6K*
dc.subject.otherlipid metabolism*
dc.subject.otherhost defense*
dc.subject.otherexercise*
dc.subject.otherkidney disease*
dc.subject.otherheat shock protein*
dc.subject.other?RIM*
dc.subject.othermycobacteria*
dc.subject.otheractivation loop*
dc.subject.otherdevelopmental origins of health and disease (DOHaD)*
dc.subject.otherCREB*
dc.subject.otherTAK1*
dc.subject.othermetabolic-inflammation*
dc.subject.otherphenylephrine*
dc.subject.otherAMP-activated protein kinase (AMPK)*
dc.subject.otherKATs*
dc.subject.other2-methoxyestradiol*
dc.subject.otherDNA methylation*
dc.subject.otherNLRP3*
dc.subject.otherpump*
dc.subject.other?-linker*
dc.subject.othersteatosis*
dc.subject.otherAMPK kinase*
dc.subject.otherstress*
dc.subject.otherendothelial nitric-oxide synthase*
dc.subject.othervasodilation*
dc.subject.otheradherent junctions*
dc.subject.otherepithelial cells*
dc.subject.otherglycogen*
dc.subject.otherAkt*
dc.subject.othersynaptic activation*
dc.subject.othercellular energy sensing*
dc.subject.otherglucose uptake*
dc.subject.othertransporter*
dc.subject.otherco-expression*
dc.subject.otheratrophy*
dc.subject.othernutrigenomics*
dc.subject.othermotility*
dc.subject.othervasoconstriction*
dc.subject.otherfatty acid oxidation*
dc.subject.otheroxidative stress*
dc.subject.otherAS160*
dc.subject.othermembrane*
dc.subject.otherhistone modification*
dc.subject.othersirtuin 1 (SIRT1)*
dc.subject.otherchromatin remodeling*
dc.subject.otherinsulin signalling*
dc.subject.otherdietary fatty acids*
dc.subject.otherULK*
dc.subject.otherCMML*
dc.subject.otheradaptive thermogenesis*
dc.subject.othermTOR*
dc.subject.otherMDS*
dc.subject.othermechanical unloading*
dc.subject.otherAML*
dc.subject.otherendothelial function*
dc.subject.othermedulloblastoma*
dc.subject.otherPKA*
dc.subject.otheradipose tissue*
dc.subject.otherNAD<sup>+</sup>*
dc.subject.othermembranes*
dc.subject.othernutrition*
dc.subject.otherZO-1*
dc.subject.otherTBC1D4*
dc.subject.otheradipocyte*
dc.subject.othersoluble Adenylyl cyclase*
dc.subject.othermetabolism*
dc.subject.otherrenin-angiotensin system*
dc.subject.otherenergy utilization*
dc.subject.otherproteasome*
dc.subject.otherdifferentiation*
dc.subject.othersignaling*
dc.subject.otherperoxisome proliferator-activated receptor gamma coactivator 1-? (PGC1?)*
dc.subject.otherhypertrophy*
dc.subject.otherAMP-activated protein kinase*
dc.subject.othermetabolic disease*
dc.subject.otherLKB1*
dc.subject.othersoleus muscle*
dc.subject.othermacrophages*
dc.subject.otherImmediate early genes*
dc.subject.otherCBS*
dc.subject.otherbeiging*
dc.subject.othermotor endplate remodeling*
dc.subject.otherionomycin*
dc.subject.othernectin-afadin*
dc.subject.othertight junctions*
dc.subject.otherresveratrol*
dc.subject.otherprotein kinase B*
dc.subject.otherregrowth*
dc.subject.othermitochondria*
dc.subject.otherprotein synthesis*
dc.subject.otherenergy deficiency*
dc.subject.othercatechol-<i>O</i>-methyltransferase*
dc.subject.otherfiber-type*
dc.subject.othermicroarrays*
dc.subject.othercarrier*
dc.subject.otheracetyl-CoA*
dc.subject.otherhypertension*
dc.subject.other3T3-L1*
dc.subject.otherhypothalamus*
dc.subject.otherfood intake*
dc.titleAMP-Activated Protein Kinase Signalling*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03897-663-9*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
oapen.relation.isbn9783038976622*
oapen.pages452*
oapen.edition1st*


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