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Computational and Experimental Approaches in Multi-Target Pharmacology

dc.contributor.authorThomas J. Anastasio*
dc.date.accessioned2021-02-11T10:18:58Z
dc.date.available2021-02-11T10:18:58Z
dc.date.issued2017*
dc.date.submitted2018-02-27 16:16:44*
dc.identifier25566*
dc.identifier.issn16648714*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/43699
dc.description.abstractThe next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.*
dc.languageEnglish*
dc.relation.ispartofseriesFrontiers Research Topics*
dc.subjectRM1-950*
dc.subjectQ1-390*
dc.subject.classificationthema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKG Pharmacologyen_US
dc.subject.othersystems biology*
dc.subject.othercomputer modeling*
dc.subject.otherdrug repurposing*
dc.subject.othersynergy*
dc.subject.otherdrug discovery*
dc.subject.otherdrug combination*
dc.subject.otherhigh throughput screening*
dc.subject.othermultidrug therapeutics*
dc.subject.otherpolypharmacy*
dc.subject.othermultifactorial process*
dc.titleComputational and Experimental Approaches in Multi-Target Pharmacology*
dc.typebook
oapen.identifier.doi10.3389/978-2-88945-252-1*
oapen.relation.isPublishedBybf5ce210-e72e-4860-ba9b-c305640ff3ae*
oapen.relation.isbn9782889452521*
oapen.pages122*


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