DNA Replication Controls

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http://www.mdpi.com/books/pdfview/book/453
Author(s)
Eishi Noguchi (Ed.)
Language
English
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Abstract
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders.
URI
https://directory.doabooks.org/handle/20.500.12854/45329
Keywords
DNA helicase; DNA replication; replication stress; replication checkpoint; DNA polymerase; telomere replication; cancer; genomic instability; DNA repair; replisome; translesion synthesis
DOI
10.3390/books978-3-03842-569-4
Webshop link
http://www.mdpi.com/books/pdfv ...
ISBN
9783038425694, 9783038425687
Publisher
MDPI - Multidisciplinary Digital Publishing Institute
Publisher website
www.mdpi.com/books
Publication date and place
2017
Classification
Biology, life sciences
Pages
X, 304
Rights
https://creativecommons.org/licenses/by-nc-nd/4.0/
https://creativecommons.org/licenses/by-nc-nd/4.0/
Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/