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MERS-CoV

dc.contributor.authorDu, Lanying*
dc.contributor.authorLi, Fang*
dc.date.accessioned2021-02-11T19:18:25Z
dc.date.available2021-02-11T19:18:25Z
dc.date.issued2019*
dc.date.submitted2020-01-07 09:08:26*
dc.identifier43226*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/53201
dc.description.abstractMiddle East respiratory syndrome coronavirus (MERS-CoV) is an emerging zoonotic coronavirus. First identified in 2012, MERS-CoV has caused over 2460 infections and a fatality rate of about 35% in humans. Similar to severe acute respiratory syndrome coronavirus (SARS-CoV), MERS-CoV likely originated from bats; however, different from SARS-CoV, which potentially utilized palm civets as its intermediate hosts, MERS-CoV likely transmits to humans through dromedary camels. Animal models, such as humanized mice and nonhuman primates, have been developed for studying MERS-CoV infection. Currently, there are no vaccines and therapeutics approved for the prevention and treatment of MERS-CoV infection, although a number of them have been developed preclinically or tested clinically. This book covers one editorial and 16 articles (including seven review articles and nine original research papers) written by researchers working in the field of MERS-CoV. It describes the following three main aspects: (1) MERS-CoV epidemiology, transmission, and pathogenesis; (2) current progress on MERS-CoV animal models, vaccines, and therapeutics; and (3) challenges and future prospects for MERS-CoV research. Overall, this book will help researchers in the MERS-CoV field to further advance their work on the virus. It also has important implications for other coronaviruses as well as viruses outside the coronavirus family with pandemic potentials.*
dc.languageEnglish*
dc.subjectQH301-705.5*
dc.subjectQ1-390*
dc.subject.classificationthema EDItEUR::P Mathematics and Science::PS Biology, life sciencesen_US
dc.subject.othercell–cell fusion*
dc.subject.otherhDPP4*
dc.subject.othern/a*
dc.subject.othertherapeutics*
dc.subject.otheranimal models*
dc.subject.otherHCoV-229E*
dc.subject.otherDrivers*
dc.subject.othercamels*
dc.subject.otherrabbits*
dc.subject.otherSARS-CoV*
dc.subject.otherMERS-CoV*
dc.subject.otherMVA vaccine*
dc.subject.othertransmission*
dc.subject.otherRBD*
dc.subject.otherMERS-CoV nucleocapsid protein*
dc.subject.othercomplement*
dc.subject.otheranimal model*
dc.subject.otherpseudotyped virus*
dc.subject.othercombination*
dc.subject.otherMERS-coronavirus*
dc.subject.otherpeptide*
dc.subject.othermouse model*
dc.subject.otherspike protein*
dc.subject.otherreceptor-binding domain*
dc.subject.otherprevention and treatment*
dc.subject.othercoronaviruses*
dc.subject.othercoronavirus spike glycoprotein*
dc.subject.othertherapeutic antibodies*
dc.subject.othervaccine platforms*
dc.subject.othermutation*
dc.subject.othersevere acute respiratory syndrome coronavirus*
dc.subject.otherpathogenesis*
dc.subject.otherfusion inhibitor*
dc.subject.otherCoronavirus*
dc.subject.othermurine CD8+ T cell epitope*
dc.subject.otherlipidomics*
dc.subject.otherauthentic virus*
dc.subject.othercorrelates of immunity*
dc.subject.othervaccines*
dc.subject.otherneutralizing monoclonal antibodies*
dc.subject.otherMiddle East respiratory syndrome coronavirus*
dc.subject.othersmall-molecule inhibitor*
dc.subject.otherMiddle East Respiratory Syndrome Virus*
dc.subject.otherDPP4*
dc.subject.otherpyroptosis*
dc.subject.othercross-neutralization*
dc.subject.otherinflammation*
dc.subject.otherQatar*
dc.subject.otherspike proteins*
dc.subject.otherOne Health*
dc.subject.otherHKU4*
dc.subject.othernanobodies*
dc.subject.othermechanism of action*
dc.subject.otherneutralizing antibody*
dc.subject.otherhost factors*
dc.subject.otherUHPLC–MS*
dc.titleMERS-CoV*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03921-851-6*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
oapen.relation.isbn9783039218509*
oapen.relation.isbn9783039218516*
oapen.pages274*
oapen.edition1st*


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Except where otherwise noted, this item's license is described as https://creativecommons.org/licenses/by-nc-nd/4.0/