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Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides

dc.contributor.authorRubattu, Speranza*
dc.contributor.authorVolpe, Massimo*
dc.date.accessioned2021-02-11T20:02:53Z
dc.date.available2021-02-11T20:02:53Z
dc.date.issued2019*
dc.date.submitted2019-12-09 11:49:16*
dc.identifier42593*
dc.identifier.urihttps://directory.doabooks.org/handle/20.500.12854/53824
dc.description.abstractThe natriuretic peptides (NPs) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. The discovery of NPs provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and kidney functions. NPs have also been implicated in the pathogenesis of several cardiovascular diseases (CVDs), including hypertension, atherosclerosis, heart failure, and stroke. A fine comprehension of the molecular mechanisms dependent from NPs and underlying the promotion of cardiovascular damage has contributed to improve our understanding of the molecular basis of all major CVDs. Finally, the opportunity to target NPs in order to develop new therapeutic tools for a better treatment of CVDs has been developed over the years. The current Special Issue of the Journal covers all major aspects of the molecular implications of NPs in physiology and pathology of the cardiovascular system, including NP-based therapeutic approaches.*
dc.languageEnglish*
dc.subjectR5-920*
dc.subjectRC666-701*
dc.subject.classificationthema EDItEUR::M Medicine and Nursingen_US
dc.subject.otherpostmortem biochemistry*
dc.subject.othermedulla*
dc.subject.otheranimal models*
dc.subject.otherremodeling*
dc.subject.otherBNP*
dc.subject.otherPCSK9*
dc.subject.otherguanylyl cyclase/natriuretic peptide receptor-A*
dc.subject.othercardiorenal syndrome*
dc.subject.otherforensic medicine*
dc.subject.otherpreserved ejection fraction*
dc.subject.otherkidney*
dc.subject.otherrenin-angiotensin-aldosterone system*
dc.subject.otheratrial fibrillation*
dc.subject.othervasopressor*
dc.subject.othercongestive heart failure*
dc.subject.otheratrial natriuretic peptide*
dc.subject.othergene-knockout*
dc.subject.otherobesity*
dc.subject.otherheart failure*
dc.subject.otherangiogenesis*
dc.subject.otheradipose tissue*
dc.subject.othervascular*
dc.subject.otherLDL receptor*
dc.subject.othermetabolic syndrome*
dc.subject.otherlinkage analysis*
dc.subject.othercardiometabolic disease*
dc.subject.othercardiomyocyte*
dc.subject.othercardiac dysfunction*
dc.subject.othercardiac hypertrophy*
dc.subject.otherinsulin*
dc.subject.otherlipid metabolism*
dc.subject.othercGMP*
dc.subject.otherIdiopathic Pulmonary Arterial Hypertension (IPAH)*
dc.subject.otherNatriuretic Peptide Clearance Receptor (NPR-C) signaling*
dc.subject.othergene-duplication*
dc.subject.otherrenin–angiotensin system*
dc.subject.othernatriuretic peptides*
dc.subject.otherangiotensin receptor–neprilysin inhibitor*
dc.subject.othercardiac remodelling*
dc.subject.otherARNi*
dc.subject.otherNT-proBNP*
dc.subject.otherinflammation*
dc.subject.otherpulmonary arterial hypertension*
dc.subject.othervascular homeostasis*
dc.subject.otherendothelial cell*
dc.subject.otherAtrial Natriuretic peptide*
dc.subject.othernatriuretic peptide*
dc.subject.othervasodilator*
dc.subject.otherstroke*
dc.subject.othergenetic variants*
dc.subject.otherarterial hypertension*
dc.subject.otherfibroblast*
dc.subject.otherMANP*
dc.subject.otherhypertension*
dc.subject.otherguanylyl cyclase receptor A*
dc.titleMolecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides*
dc.typebook
oapen.identifier.doi10.3390/books978-3-03921-583-6*
oapen.relation.isPublishedBy46cabcaa-dd94-4bfe-87b4-55023c1b36d0*
oapen.relation.isbn9783039215836*
oapen.relation.isbn9783039215829*
oapen.pages212*
oapen.edition1st*


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