Synthetic and Biosynthetic Approaches to Marine Natural Products

Barbero, Asunción

doi:10.3390/books978-3-03928-467-2

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https://mdpi.com/books/pdfview/book/2122

Author(s)

Barbero, Asunción

Language

English

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Abstract

Marine natural products containing a heterocyclic moiety in their structure are present in a wide variety of sponges, corals, algae, and fungi. Many of them show important biological activities such as cytotoxic properties against several cancer cell lines. Their challenging chemical structures have attracted the attention of many researchers who have developed various synthetic approaches. This Special Issue presents some examples of new synthetic or biosynthetic methodologies to access this type of marine natural drug.

URI

https://directory.doabooks.org/handle/20.500.12854/60412

Keywords

antarctic-derived fungus; marine drugs analogues; antitumor; pallescensone; Haematococcus pluvialis; toluquinol; antiproliferative activity; astaxanthin; thymoquinone; alotamide; microalgae; tetrahydropyrans; isomicrocionin-3; hybrid polyketides; anticonvulsant; peptide/polyketide molecules; functional-analogues; Synechococcus sp. PCC 7942; natural compound analogues; LLC-PK1 cells; structural modification; relative structural determination; benzo[d]thiazol; Cladosporium sphaerospermum; hybrid PKS-NRPS; anticandidal activity; Octopus minor; dihydropallescensin 2; Candida albicans; Iso-Seq; biological activity; Octominin; pallescensin 2; pallescensin 1; stereoselective; synthetic analogues; psammaplin A; cyclogeranylsulfonylbenzene isomers; synthesis; smenamides; MM cell line; ?-ketoacyl ACP Synthase; antidepressant; marine natural products; marine hydroquinone; tetramic acid; asymmetric synthesis; acid mediated cyclization; stereoselective synthesis; GGPPS; furanosesquiterpenes; marine natural product; short chain fatty acids; antimicrobial peptides; lipase-mediated resolution