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            Chapter Genomes

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            Author(s)
            Harb, Omar
            Boehme, Ulrike
            Crouch, Kathryn
            Ifeonu, Olukemi
            Roos, David
            Silva, Joana
            Silva-Franco, Fatima
            Svärd, Staffan
            Tretina, Kyle
            Weedall, Gareth
            Collection
            Wellcome
            Language
            English
            Show full item record
            Abstract
            In the last decade, the rise of affordable affordable high-throughput sequencing technologies has led to rapid advances across the biological sciences. At the time of writing, annotated reference genomes are available within most clades of eukaryotic pathogens, and including un-annotated sequences over 550 genomes are available in total. This This has greatly facilitated studies in many areas of parasitology. In addition, the volume of functional genomics data, including analysis of differential differential transcription and DNA-protein interactions, has increased exponentially. With this unprecedented increase in publicly available data, tools to search and compare datasets are also becoming ever more important. A number of database resources are available, and access to these has become fundamental for a majority of research groups. This This chapter discusses the current state of genomics research for a number of eukaryotic parasites, discussing the genome and functional genomics resources available at the time of writing and highlighting functionally important or unique aspects of the genome for each group. In addition publicly accessible database resources pertaining to eukaryotic parasites are also discussed.
            Book
            Molecular Parasitology
            URI
            https://doab-dev.siscern.org/handle/20.500.12854/175864
            Keywords
            biological sciences; genomes; parasitology; genomics research; eukaryotic parasites; thema EDItEUR::M Medicine and Nursing::MK Medical specialties, branches of medicine::MKF Pathology::MKFP Medical parasitology
            ISBN
            9783709114155, 9783709148792
            Publisher
            Springer Nature
            Publisher website
            http://www.springernature.com/oabooks
            Publication date and place
            2016
            Grantor
            • Wellcome Trust
            Pages
            37
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            • logo EUEuropean Union
              This project received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 871069.

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